The role of the lung microbiota and the gut–lung axis in respiratory infectious diseases

A Dumas, L Bernard, Y Poquet… - Cellular …, 2018 - Wiley Online Library
The pulmonary microbial community, described only a few years ago, forms a discreet part
of the human host microbiota. The airway microbiota has been found to be substantially …

The potential application of probiotics and prebiotics for the prevention and treatment of COVID-19

AN Olaimat, I Aolymat, M Al-Holy, M Ayyash… - npj Science of …, 2020 - nature.com
COVID-19 is a pandemic disease caused by the novel coronavirus severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). This new viral infection was first identified in China …

Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024 - nature.com
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Probiotics: A potential immunomodulator in COVID-19 infection management

K Singh, A Rao - Nutrition Research, 2021 - Elsevier
COVID-19 caused by SARS-CoV-2 is an ongoing global pandemic. SARS-CoV-2 affects the
human respiratory tract's epithelial cells, leading to a proinflammatory cytokine storm and …

The Beneficial Role of Probiotic Lactobacillus in Respiratory Diseases

T Du, A Lei, N Zhang, C Zhu - Frontiers in immunology, 2022 - frontiersin.org
Respiratory diseases cause a high incidence and mortality worldwide. As a natural
immunobiotic, Lactobacillus has excellent immunomodulatory ability. Administration of some …

Modulation of pulmonary microbiota by antibiotic or probiotic aerosol therapy: a strategy to promote immunosurveillance against lung metastases

V Le Noci, S Guglielmetti, S Arioli, C Camisaschi… - Cell reports, 2018 - cell.com
Pulmonary immunological tolerance to inhaled particulates might create a permissive milieu
for lung metastasis. Lung microbiota contribute to pulmonary tolerance; here, we explored …

Engineering DNA vaccines against infectious diseases

J Lee, SA Kumar, YY Jhan, CJ Bishop - Acta Biomaterialia, 2018 - Elsevier
Engineering vaccine-based therapeutics for infectious diseases is highly challenging, as
trial formulations are often found to be nonspecific, ineffective, thermally or hydrolytically …

Serial analysis of the gut and respiratory microbiome in cystic fibrosis in infancy: interaction between intestinal and respiratory tracts and impact of nutritional …

JC Madan, DC Koestler, BA Stanton, L Davidson… - MBio, 2012 - Am Soc Microbiol
Pulmonary damage caused by chronic colonization of the cystic fibrosis (CF) lung by
microbial communities is the proximal cause of respiratory failure. While there has been an …

Probiotics in treatment of viral respiratory infections and neuroinflammatory disorders

R Shahbazi, H Yasavoli-Sharahi, N Alsadi, N Ismail… - Molecules, 2020 - mdpi.com
Inflammation is a biological response to the activation of the immune system by various
infectious or non-infectious agents, which may lead to tissue damage and various diseases …

Host factors impact vaccine efficacy: implications for seasonal and universal influenza vaccine programs

S Dhakal, SL Klein - Journal of virology, 2019 - Am Soc Microbiol
Influenza is a global public health problem. Current seasonal influenza vaccines have highly
variable efficacy, and thus attempts to develop broadly protective universal influenza …