Defining biotypes for depression and anxiety based on large‐scale circuit dysfunction: A theoretical review of the evidence and future directions for clinical translation
LM Williams - Depression and anxiety, 2017 - Wiley Online Library
Complex emotional, cognitive and self‐reflective functions rely on the activation and
connectivity of large‐scale neural circuits. These circuits offer a relevant scale of focus for …
connectivity of large‐scale neural circuits. These circuits offer a relevant scale of focus for …
Integrated neurobiology of bipolar disorder
V Maletic, C Raison - Frontiers in psychiatry, 2014 - frontiersin.org
From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is
almost certainly the case that many somewhat similar, but subtly different, pathological …
almost certainly the case that many somewhat similar, but subtly different, pathological …
Meta-analyses of the n-back working memory task: fMRI evidence of age-related changes in prefrontal cortex involvement across the adult lifespan
Working memory, a fundamental cognitive function that is highly dependent on the integrity
of the prefrontal cortex, is known to show age-related decline across the typical healthy adult …
of the prefrontal cortex, is known to show age-related decline across the typical healthy adult …
Methodological recommendations for cognition trials in bipolar disorder by the International Society for Bipolar Disorders Targeting Cognition Task Force
Objectives To aid the development of treatment for cognitive impairment in bipolar disorder,
the International Society for Bipolar Disorders (ISBD) convened a task force to create a …
the International Society for Bipolar Disorders (ISBD) convened a task force to create a …
A neurobiological approach to the cognitive deficits of psychiatric disorders
Deficits in brain networks that support cognitive regulatory functions are prevalent in many
psychiatric disorders. Findings across neuropsychology and neuroimaging point to broad …
psychiatric disorders. Findings across neuropsychology and neuroimaging point to broad …
[HTML][HTML] The role of dlPFC laterality in the expression and regulation of anxiety
Anxiety disorders are the most common mental health disorder. Therefore, elucidating brain
mechanisms implicated in anxiety disorders is important avenue for developing novel …
mechanisms implicated in anxiety disorders is important avenue for developing novel …
Differentiating unipolar and bipolar depression by alterations in large‐scale brain networks
R Goya‐Maldonado, K Brodmann, M Keil… - Human brain …, 2016 - Wiley Online Library
Background Misdiagnosing bipolar depression can lead to very deleterious consequences
of mistreatment. Although depressive symptoms may be similarly expressed in unipolar and …
of mistreatment. Although depressive symptoms may be similarly expressed in unipolar and …
Altered patterns of central executive, default mode and salience network activity and connectivity are associated with current and future depression risk in two …
Neural markers of pathophysiological processes underlying the dimension of subsyndromal-
syndromal-level depression severity can provide objective, biologically informed targets for …
syndromal-level depression severity can provide objective, biologically informed targets for …
Eye movement desensitization and reprocessing therapy in subsyndromal bipolar patients with a history of traumatic events: a randomized, controlled pilot-study
P Novo, R Landin-Romero, J Radua, V Vicens… - Psychiatry …, 2014 - Elsevier
Traumatic events are frequent in bipolar patients and can worsen the course of the disease.
Psychotherapeutic interventions for these events have not been studied so far. Twenty DSM …
Psychotherapeutic interventions for these events have not been studied so far. Twenty DSM …
Evidence for structural and functional abnormality in the subgenual anterior cingulate cortex in major depressive disorder
Background. The subgenual anterior cingulate cortex (sgACC) is considered to be an
important site of abnormality in major depressive disorder. However, structural alterations in …
important site of abnormality in major depressive disorder. However, structural alterations in …