The fibroblast growth factor signaling pathway

DM Ornitz, N Itoh - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …

[HTML][HTML] Keratinocyte–fibroblast interactions in wound healing

S Werner, T Krieg, H Smola - Journal of investigative dermatology, 2007 - Elsevier
Cutaneous tissue repair aims at restoring the barrier function of the skin. To achieve this,
defects need to be replaced by granulation tissue to form new connective tissue, and …

Research resource: comprehensive expression atlas of the fibroblast growth factor system in adult mouse

K Fon Tacer, AL Bookout, X Ding… - Molecular …, 2010 - academic.oup.com
Although members of the fibroblast growth factor (FGF) family and their receptors have well-
established roles in embryogenesis, their contributions to adult physiology remain relatively …

[PDF][PDF] Wound re-epithelialization: modulating keratinocyte migration in wound healing

SK Raja, MS Garcia, RR Isseroff - Front Biosci, 2007 - academia.edu
An essential feature of a healed wound is the restoration of an intact epidermal barrier
through wound epithelialization, also known as re-epithelialization. The directed migration of …

The roles of growth factors in keratinocyte migration

MA Seeger, AS Paller - Advances in wound care, 2015 - liebertpub.com
Significance: The re-epithelialization of wounded skin requires the rapid and coordinated
migration of keratinocytes (KC) into the wound bed. Almost immediately after wounding …

FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain

H Umemori, MW Linhoff, DM Ornitz, JR Sanes - Cell, 2004 - cell.com
Target-derived cues promote local differentiation of axons into nerve terminals at sites of
synaptic contact. Using clustering of synaptic vesicles in cultured neurons as an assay, we …

Keratinocyte growth factor/fibroblast growth factor 7, a homeostatic factor with therapeutic potential for epithelial protection and repair.

PW Finch, JS Rubin - Advances in cancer research, 2004 - europepmc.org
Keratinocyte growth factor (KGF) is a paracrine-acting, epithelial mitogen produced by cells
of mesenchymal origin. It is a member of the fibroblast growth factor (FGF) family, and acts …

Novel aspects of corneal angiogenic and lymphangiogenic privilege

D Ellenberg, DT Azar, JA Hallak, F Tobaigy… - Progress in retinal and …, 2010 - Elsevier
In this article, we provide the results of experimental studies demonstrating that corneal
avascularity is an active process involving the production of anti-angiogenic factors, which …

A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning

A Petiot, FJA Conti, R Grose, JM Revest… - 2003 - journals.biologists.com
To understand the role Fgf signalling in skin and hair follicle development, we analysed the
phenotype of mice deficient for Fgfr2-IIIb and its main ligand Fgf10. These studies showed …

[HTML][HTML] Comprehensive analysis of FGF and FGFR expression in skin: FGF18 is highly expressed in hair follicles and capable of inducing anagen from telogen stage …

M Kawano, A Komi-Kuramochi, M Asada… - Journal of Investigative …, 2005 - Elsevier
We quantified the mRNA expression of all 22 fibroblast growth factor family members (FGF)
and their four receptors (FGFR) in adult mouse full-thickness skin at various stages of the …