Rituximab-associated infections

JC Gea-Banacloche - Seminars in hematology, 2010 - Elsevier
After more than 10 years of use, rituximab has proven to be remarkably safe. However,
accumulated evidence now suggests that under some circumstances it may significantly …

Consequences of B-cell-depleting therapy: hypogammaglobulinemia and impaired B-cell reconstitution

KA Sacco, RS Abraham - Immunotherapy, 2018 - Taylor & Francis
Rituximab is a chimeric monoclonal antibody used to treat hematologic and autoimmune
diseases by depleting CD20-expressing B cells. Patients may develop …

[HTML][HTML] Practical guidance for the diagnosis and management of secondary hypogammaglobulinemia: A Work Group Report of the AAAAI Primary Immunodeficiency …

IM Otani, HK Lehman, AM Jongco, LR Tsao… - Journal of Allergy and …, 2022 - Elsevier
Secondary hypogammaglobulinemia (SHG) is characterized by reduced immunoglobulin
levels due to acquired causes of decreased antibody production or increased antibody loss …

Rituximab-associated hypogammaglobulinemia: incidence, predictors and outcomes in patients with multi-system autoimmune disease

DM Roberts, RB Jones, RM Smith, F Alberici… - Journal of …, 2015 - Elsevier
Rituximab is a B cell depleting monoclonal antibody used to treat lymphoma and
autoimmune disease. Hypogammaglobulinemia has occurred after rituximab for lymphoma …

Incidence of hypogammaglobulinemia in patients receiving rituximab and the use of intravenous immunoglobulin for recurrent infections

C Casulo, J Maragulia, AD Zelenetz - Clinical Lymphoma Myeloma and …, 2013 - Elsevier
Background Rituximab has altered the treatment approach to B-cell malignancies and other
diseases. Reports consider that rituximab had limited impact on serum immunoglobulins …

The effect of rituximab therapy on immunoglobulin levels in patients with multisystem autoimmune disease

H Marco, RM Smith, RB Jones, MJ Guerry… - BMC musculoskeletal …, 2014 - Springer
Background Rituximab is a B cell depleting anti-CD20 monoclonal antibody. CD20 is not
expressed on mature plasma cells and accordingly rituximab does not have immediate …

Hypogammaglobulinaemia after rituximab treatment—incidence and outcomes

M Makatsori, S Kiani-Alikhan, AL Manson… - … Journal of Medicine, 2014 - academic.oup.com
Background: Rituximab, a chimeric monoclonal antibody against CD20, is increasingly used
in the treatment of B-cell lymphomas and autoimmune conditions. Transient peripheral B …

Post-rituximab immunoglobulin M (IgM) hypogammaglobulinemia

K Kridin, AR Ahmed - Autoimmunity reviews, 2020 - Elsevier
Rituximab is a B cell depleting monoclonal antibody that targets the B cell-specific cell
surface antigen CD20 and is currently used to treat several autoimmune diseases. The …

Rituximab maintenance for the treatment of patients with follicular lymphoma: an updated systematic review and meta-analysis of randomized trials

L Vidal, A Gafter-Gvili, G Salles… - Journal of the …, 2011 - academic.oup.com
In a previous systematic review and meta-analysis of five randomized controlled trials
comparing rituximab maintenance with no maintenance (observation or rituximab at …

Rituximab purging and/or maintenance in patients undergoing autologous transplantation for relapsed follicular lymphoma: a prospective randomized trial from the …

R Pettengell, N Schmitz, C Gisselbrecht… - Journal of clinical …, 2013 - ascopubs.org
Purpose The objective of this randomized trial was to assess the efficacy and safety of
rituximab as in vivo purging before transplantation and as maintenance treatment …