Pentoxifylline and thiamine ameliorate rhabdomyolysis-induced acute kidney injury in rats via suppressing TLR4/NF-κB and NLRP-3/caspase-1/gasdermin mediated …

L Al-Kharashi, H Attia, A Alsaffi, T Almasri… - Toxicology and Applied …, 2023 - Elsevier
Acute kidney injury (AKI) is a common complication of rhabdomyolysis (RM), a syndrome
characterized by skeletal muscle damage resulting in renal tubular oxidative stress …

[HTML][HTML] The polarization of M2 macrophages can be adjusted to alleviate renal injury by methylprednisolone in sepsis-AKI

K Ma, JF Liu, ZR Zheng, HY Li, B Hu, Y Meng - Archives of Biochemistry …, 2023 - Elsevier
Acute kidney injury in sepsis patients has an extreme mortality rate in clinical. It obviously
seems that immune cells, for example, macrophages are involved with this process …

Molecular mechanisms and pathophysiology of ischemia-reperfusion injury

A Panisello-Roselló, J Roselló-Catafau - International Journal of …, 2018 - mdpi.com
Ischemia-reperfusion injury (IRI) is a major cause of graft loss and dysfunction in clinical
transplantation and organ resection. The predominant focus on immunological rejection in …

Evaluation of Nrf2/ARE signaling pathway in the presence of pentoxifylline as a cryoprotectant in mouse spermatogonial stem cells

G Sadeghiani, M Khanehzad… - Biopreservation and …, 2023 - liebertpub.com
The process of spermatogonial stem cell cryopreservation (SSCs) in young male cancer
survivors is associated with increased reactive oxygen species (ROS), DNA fragmentation …

Effects of grape seed-derived proanthocyanidin B2 pretreatment on oxidative stress, endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells in …

Z Wang, B Shu, Q Han, G Li, Y Guo - International Urology and Nephrology, 2023 - Springer
Purpose To investigate the effect of grape seed-derived proanthocyanidin B2 (GSPB2)
pretreatment on acute renal ischemia–reperfusion injury model of mice. Methods 50 mice …

Implications of miRNAs on TGF-β/TAK1/mTOR pathway in mediating the renoprotective effects of pentoxifylline against cisplatin-induced nephrotoxicity in rats

M Hekmat, MF Schaalan, RM Rahmo, DB Farag… - Toxicology and Applied …, 2020 - Elsevier
Cisplatin (CIS)-mediated nephrotoxicity is induced via transforming growth factor-beta (TGF-
β) and TGF-β-activated kinase (TAK1). TGF-β and TAK1 are known to interact with …

[PDF][PDF] 结扎大鼠肾动静脉所致急性肾损伤模型的研究

龚琴, 王木兰, 左沙沙, 张远利, 许溪, 何鹿玲… - 中国中药 …, 2019 - researchgate.net
《中国中药杂志》网络首发论文 Page 1 中国中药杂志 China Journal of Chinese Materia Medica
ISSN 1001-5302,CN 11-2272/R 《中国中药杂志》网络首发论文 题目: 结扎大鼠肾动静脉所致急性 …

Protective effect of quercetin on renal tubular cells and the involvement with the renin-angiotensin-aldosterone Axis

JA Canuto, TL Sampaio, ME Silva… - Brazilian Archives of …, 2021 - SciELO Brasil
Abstract Ischemia-reperfusion (I/R) plays an important role in the process of acute kidney
injury (AKI) due to the generation of reactive oxygen species (ROS). Substances of natural …

Protective effects of methylprednisolone in kidney: aortic occlusion-reperfusion model in rats

S Seçici, KK Özsin, M özgür Özyiğit, O Arda… - The European …, 2023 - dergipark.org.tr
Objectives: Ischemia/reperfusion (I/R) injury is commonly seen in cardiovascular surgery,
activates inflammation and causes renal damage. In this experimental study, we aimed to …

Comparison of the protective effects of betamethasone, dexamethasone and methylprednisolone in ischemia/reperfusion injury of rat ovary

AD Anğın, MA Oruç, Ö Sakin, K Koyuncu… - … of Experimental and …, 2020 - dergipark.org.tr
AbstractObjectivesOur aim is to evaluate the protective effect of dexamethasone,
methylprednisolone and betamethasone treatment against ischemia-reperfusion damage …