Lentiviral vectors (LVs), derived from human immunodeficiency virus, are powerful tools for
modifying the genes of eukaryotic cells such as hematopoietic stem cells and neural cells …

Mitochondria's role as engines and beacons of metabolism and determinants of cellular
health is being redefined through their therapeutic application as “Living Drugs”(LDs) …

Over the last decade, CRISPR has revolutionized drug development due to its potential to
cure genetic diseases that currently do not have any treatment. CRISPR was adapted from …

Since first proposed as a new tool for gene targeting and genome editing, CRISPR
technology has quickly advanced into the clinical stage. Initial studies highlight the potential …

Japan's Act on the Safety of Regenerative Medicine (ASRM) created an innovative
regulatory framework intended to safely promote the clinical development of stem cell-based …

Gene or genome editing (GE) revises, removes, or replaces a mutated gene at the DNA
level; it is a tool. Gene therapy (GT) offsets mutations by introducing a “normal” version of the …

Somatic gene editing (SGE) holds great promise for making genetic therapy possible for
many monogenic conditions very soon. Is our current system of European market …

Definition Gene or genome editing, often known as GE, is a technique utilized to modify,
eliminate, or substitute a mutated gene at the DNA level. It serves as a valuable tool in the …

Summary Three‐dimensional (3D) bioprinting is revolutionizing the medical industry.
Bioprinting could help overcome the limitations of organ transplant waiting times and …

Gene therapy is the treatment of abnormal or mutated genes present in cells through the
addition of healthy genes or replacement/deletion/site-specific modification of faulty genes …