Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

Senile depression (SD) is a heterogeneous syndrome. Several clinical profiles are more
likely to appear in SD than in early‐life depression, but it remains unclear whether the …

Patients with late-onset Alzheimer's disease (LOAD) frequently manifest comorbid
neuropsychiatric symptoms with depression and anxiety being most frequent, and …

Background Although many studies reported a close relationship between depression and
Alzheimer's disease (AD), the underlying pathophysiological mechanism remains unclear …

Background: Several etiologies can underlie the development of late-onset psychosis,
defined by first psychotic episode after age 40 years. Late-onset psychosis is distressing to …

It remains unclear whether psychotic depression (PD) compared to non-psychotic
depression (non-PD) among older adults is associated with poorer cognitive performance …

The extent and nature of cognitive impairment in brief psychotic disorder remains unclear,
being rarely studied unlike schizophrenia. The present study hence sought to directly …

Even though psychotic depression is related to worse outcomes than nonpsychotic
depression, there is increasing evidence that this greater severity is not solely explained by …

目的了解河南省失能老年人抑郁现状及其影响因素, 为今后养老工作的开展提供建议及参考.
方法于2019 年1—3 月采用多阶段随机抽样方法对在河南省18 个省辖市抽取的5 570 名≥ 60 …

The current study validated and compared three short Geriatric Depression Scales (GDS),
including the GDS-5, D'Ath GDS-4, and van Marwijk GDS-4, among 917 Chinese community …