Metastasis accounts for 90% of breast cancer mortality. Despite the significant progress
made over the past decade in cancer medicine our understanding of metastasis remains …

An early diagnosis of hepatocellular carcinoma (HCC) followed by effective treatment is
currently critical for improving the prognosis and reducing the associated economic burden …

When cancer metastasizes to bone, considerable pain and deregulated bone remodelling
occurs, greatly diminishing the possibility of cure. Metastasizing tumour cells mobilize and …

Osteopontin (OPN) also known by its official gene designation secreted phosphoprotein‐1
(SPP1) is a fascinating, multifunctional protein expressed in a number of cell types that …

Organ-specific metastasis is the primary cause of cancer patient death. The distant
metastasis of tumor cells to specific organs depends on both the intrinsic characteristics of …

Metastasis to bone frequently occurs in majority of patients with advanced breast cancer and
prostate cancer, leading to devastating skeletal-related events and substantially reducing …

The aim of this study was to identify a biomarker that could improve alpha‐fetoprotein (AFP)
performance in hepatocellular carcinoma (HCC) surveillance among patients with cirrhosis …

Integrins are a large family of transmembrane adhesion receptors, which play a key role in
interactions of a cell with the surrounding stroma. Integrins are comprised of non-covalently …

Complex interactions between tumor and host cells regulate systemic tumor dissemination,
a process that begins early at the primary tumor site and goes on until tumor cells detach …

The bottleneck arising from castration‐resistant prostate cancer (CRPC) treatment is its high
metastasis potential and antiandrogen drug resistance, which severely affects survival time …