The value of antimicrobial peptides in the age of resistance

M Magana, M Pushpanathan, AL Santos… - The lancet infectious …, 2020 - thelancet.com
Accelerating growth and global expansion of antimicrobial resistance has deepened the
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …

[HTML][HTML] Chemical modifications to increase the therapeutic potential of antimicrobial peptides

Y Han, M Zhang, R Lai, Z Zhang - Peptides, 2021 - Elsevier
The continued use of antibiotics has been accompanied by the rapid emergence and spread
of antibiotic-resistant strains of bacteria. Antimicrobial peptides (AMPs), also known as host …

DBAASP v3: database of antimicrobial/cytotoxic activity and structure of peptides as a resource for development of new therapeutics

M Pirtskhalava, AA Amstrong, M Grigolava… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is an
open-access, comprehensive database containing information on amino acid sequences …

APD3: the antimicrobial peptide database as a tool for research and education

G Wang, X Li, Z Wang - Nucleic acids research, 2016 - academic.oup.com
The antimicrobial peptide database (APD, http://aps. unmc. edu/AP/) is an original database
initially online in 2003. The APD2 (2009 version) has been regularly updated and further …

Antimicrobial peptides from plants

JP Tam, S Wang, KH Wong, WL Tan - Pharmaceuticals, 2015 - mdpi.com
Plant antimicrobial peptides (AMPs) have evolved differently from AMPs from other life
forms. They are generally rich in cysteine residues which form multiple disulfides. In turn, the …

Antimicrobial peptides of multicellular organisms: my perspective

M Zasloff - Antimicrobial Peptides: Basics for Clinical Application, 2019 - Springer
Antimicrobial peptides of multicellular organisms were first characterized in the 1980s by
investigators who felt that known systems of immunity could not explain what they observed …

LAMP: a database linking antimicrobial peptides

X Zhao, H Wu, H Lu, G Li, Q Huang - PloS one, 2013 - journals.plos.org
The frequent emergence of drug-resistant bacteria has created an urgent demand for new
antimicrobial agents. Traditional methods of novel antibiotic development are almost …

A review of artificial intelligence applications for antimicrobial resistance

J Lv, S Deng, L Zhang - Biosafety and Health, 2021 - mednexus.org
The wide use and abuse of antibiotics could make antimicrobial resistance (AMR) an
increasingly serious issue that threatens global health and imposes an enormous burden on …

DBAASP v. 2: an enhanced database of structure and antimicrobial/cytotoxic activity of natural and synthetic peptides

M Pirtskhalava, A Gabrielian, P Cruz… - Nucleic acids …, 2016 - academic.oup.com
Antimicrobial peptides (AMPs) are anti-infectives that may represent a novel and untapped
class of biotherapeutics. Increasing interest in AMPs means that new peptides (natural and …

CAMP: Collection of sequences and structures of antimicrobial peptides

FH Waghu, L Gopi, RS Barai, P Ramteke… - Nucleic acids …, 2014 - academic.oup.com
Antimicrobial peptides (AMPs) are gaining importance as anti-infective agents. Here we
describe the updated Collection of Antimicrobial Peptide (CAMP) database, available online …