Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Small molecule as fluorescent probes for monitoring intracellular enzymatic transformations

H Singh, K Tiwari, R Tiwari, SK Pramanik… - Chemical …, 2019 - ACS Publications
All cellular processes are the results of synchronized actions of several intracellular
biochemical pathways. Recent emphasis is to visualize such pathways using appropriate …

Ferroptosis‐enhanced cancer immunity by a ferrocene‐appended iridium (III) Diphosphine complex

WJ Wang, YY Ling, YM Zhong, ZY Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Ferroptosis is a programmed cell death pathway discovered in recent years, and ferroptosis‐
inducing agents have great potential as new antitumor candidates. Here, we report a IrIII …

Photochromic fluorescent probe strategy for the super-resolution imaging of biologically important biomarkers

X Chai, HH Han, AC Sedgwick, N Li… - Journal of the …, 2020 - ACS Publications
Here, we report a β-galactosidase (β-Gal)-responsive photochromic fluorescent probe, NpG,
that was designed to prebind to human serum albumin (HSA) to form the probe/protein …

Responsive metal complex probes for time-gated luminescence biosensing and imaging

R Zhang, J Yuan - Accounts of chemical research, 2020 - ACS Publications
Conspectus The development of reliable bioanalytical probes for selective and sensitive
detection of particular analytes in biological systems is essential for better understanding the …

Directionally in situ self-assembled iridium (III)-polyimine complex-encapsulated metal–organic framework two-dimensional nanosheet electrode to boost …

H Qi, Z Wang, H Li, F Li - Analytical Chemistry, 2023 - ACS Publications
Manufacturing electrochemiluminescence (ECL) electrodes to detect analytes with high
performance in the aqueous phase for water-insoluble metal complexes is a great …

Solvent-dependent carbon dots and their applications in the detection of water in organic solvents

D Chao, W Lyu, Y Liu, L Zhou, Q Zhang… - Journal of Materials …, 2018 - pubs.rsc.org
In this study, solvent-dependent emitting carbon dots (CDs) were synthesized by simple one-
step hydrothermal treatment of o-phenylenediamine (oPD). The as-prepared carbon dots (o …

Single‐Cell Quantification of a Highly Biocompatible Dinuclear Iridium (III) Complex for Photocatalytic Cancer Therapy

Z Fan, Y Rong, T Sadhukhan, S Liang, W Li… - Angewandte …, 2022 - Wiley Online Library
Quantifying the content of metal‐based anticancer drugs within single cancer cells remains
a challenge. Here, we used single‐cell inductively coupled plasma mass spectrometry to …

Advances in the development of fluorescence probes for cell plasma membrane imaging

C Liu, X Gao, J Yuan, R Zhang - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Cell plasma membrane, the boundary between an individual live cell and its
microenvironment, plays important roles in cellular communication and signaling, and …

Dual function luminescent transition metal complexes for cancer theranostics: The combination of diagnosis and therapy

CN Ko, G Li, CH Leung, DL Ma - Coordination Chemistry Reviews, 2019 - Elsevier
Cancer is an aggressive disease involving abnormal cell growth with the potential to invade
other parts of the body. Despite intense interest from clinicians and biomedical researchers …