The retinal pigment epithelium is a fundamental component of the retina that plays essential
roles in visual functions. Damage to the structure and function of the retinal pigment …

The retina is a complex tissue with multiple cell layers that are highly ordered. Its
sophisticated structure makes it especially sensitive to external or internal perturbations that …

The retina is an immune privileged tissue, which is protected from external and internal
insults by its blood-retina barriers and immune suppressive microenvironment. Apart from …

Cell replacement therapy is a promising treatment for irreversible retinal cell death in diverse
diseases, such as age-related macular degeneration (AMD), Stargardt's disease, retinitis …

Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the
older population. Classical hallmarks of early and intermediate AMD are accumulation of …

The central goal of regenerative medicine is to replace damaged or diseased tissue with
cells that integrate and function optimally. The capacity of pluripotent stem cells to produce …

There have been numerous types of animal models of choroidal neovascularization (CNV)
and retinal neovascularization (RNV). Understanding the pathobiology of CNV and RNV is …

Age-related macular degeneration (AMD) is the leading cause of blindness among the
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …

Friendly and dangerous signals: is the tissue in control? | Nature Immunology Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Stem cell-derived retinal pigment epithelium (RPE) and photoreceptors (PRs) have restored
vision in preclinical models of human retinal degenerative disease. This review discusses …