Solutions to the drawbacks of photothermal and photodynamic cancer therapy

X Deng, Z Shao, Y Zhao - Advanced Science, 2021 - Wiley Online Library
Phototherapy such as photothermal therapy and photodynamic therapy in cancer treatment
has been developed quickly over the past few years for its noninvasive nature and high …

Nonreplicating adenoviral vectors: improving tropism and delivery of cancer gene therapy

NG Tessarollo, ACM Domingues, F Antunes, JCS Luz… - Cancers, 2021 - mdpi.com
Simple Summary The treatment of cancer has progressed greatly with the advent of
immunotherapy and gene therapy, including the use of nonreplicating adenoviral vectors to …

Ecto-Calreticulin is essential for an efficient immunogenic cell death stimulation in mouse melanoma

P Giglio, M Gagliardi, R Bernardini, M Mattei… - Genes & …, 2019 - nature.com
Skin melanoma remains one of the most aggressive and difficult to treat human malignancy,
with an increasing incidence every year. Although surgical resection represents the best …

Combined p14ARF and Interferon-β Gene Transfer to the Human Melanoma Cell Line SK-MEL-147 Promotes Oncolysis and Immune Activation

OLD Cerqueira, MA Clavijo-Salomon… - Frontiers in …, 2020 - frontiersin.org
Immune evasion is an important cancer hallmark and the understanding of its mechanisms
has generated successful therapeutic approaches. Induction of immunogenic cell death …

Perspectives for combining viral oncolysis with additional immunotherapies for the treatment of melanoma

OLD Cerqueira, F Antunes, NG Assis… - Frontiers in Molecular …, 2022 - frontiersin.org
Melanoma is the deadliest type of skin cancer with steadily increasing incidence worldwide
during the last few decades. In addition to its tumor associated antigens (TAAs), melanoma …

Exploration of p53 plus interferon-beta gene transfer for the sensitization of human colorectal cancer cell lines to cell death

PR Del Valle, SA Mendonça, F Antunes… - Cancer Biology & …, 2021 - Taylor & Francis
While treatments for colorectal cancer continue to improve, some 50% of patients succumb
within 5 years, pointing to the need for additional therapeutic options. We have developed a …

Perspectives for cancer immunotherapy mediated by p19Arf plus interferon-beta gene transfer

BE Strauss, GRO Silva, I de Luna Vieira… - Clinics, 2018 - SciELO Brasil
While cancer immunotherapy has gained much deserved attention in recent years, many
areas regarding the optimization of such modalities remain unexplored, including the …

Estabelecimento de linhagens celulares de melanoma canino e transdução com vetores adenovirais aprimorados

GRO Silva - 2019 - teses.usp.br
NTRODUÇÃO: O melanoma é um câncer de alta mortalidade tanto na medicina quanto na
veterinária, devido à baixa resposta às terapias utilizadas e à capacidade de evolução …

Avaliação dos efeitos autócrino e parácrino da terapia gênica com adenovírus portador de IFNbeta e sua relaçao com IFNAR1 no melanoma e microambiente murino

IL Vieira - 2021 - teses.usp.br
O câncer é uma doença complexa, frequentemente sem cura e que está presente em todas
as populações e em todas as idades. O câncer gera enormes perdas econômicas e …

p19Arf sensitizes B16 melanoma cells to interferon-β delivered via mesenchymal stem cells in vitro

RC Da-Costa, IL Vieira, A Hunger… - Brazilian Journal of …, 2020 - SciELO Brasil
The immune stimulatory and anti-neoplastic functions of type I interferon have long been
applied for the treatment of melanoma. However, the systemic application of high levels of …