The immune system recognizes a multitude of innocuous antigens from food and intestinal
commensal microbes toward which it orchestrates appropriate, non-inflammatory responses …

Group 1 innate lymphoid cells (ILC1s) are cytotoxic and interferon gamma-producing
lymphocytes lacking antigen-specific receptors, which include ILC1s and natural killer (NK) …

Besides its canonical role in protecting the host from pathogens, the immune system plays
an arguably equally important role in maintaining tissue homeostasis. Within barrier tissues …

OBJECTIVE To explore if oral insulin could delay onset of stage 3 type 1 diabetes (T1D)
among patients with stage 1/2 who carry HLA DR4-DQ8 and/or have elevated levels of IA-2 …

Group 3 innate lymphoid cells (ILC3s) are abundant in the developing or healthy intestine to
critically support tissue homeostasis in response to microbial colonization. However …

Conventional dendritic cells (cDC) are antigen-presenting cells comprising cDC1 and cDC2,
responsible for priming naive CD8+ and CD4+ T cells, respectively. Recent studies have …

Conventional dendritic cells (cDCs) are sentinels of the mammalian immune system that
sense a wide range of danger and homeostatic signals to induce appropriately targeted T …

The gastrointestinal tract is continuously exposed to foreign antigens in food and
commensal microbes with potential to induce adaptive immune responses. Peripherally …

The gut microbiota is well known to possess immunomodulatory capacities, influencing a
multitude of cellular signalling pathways to maintain host homeostasis. Although the …

Innate lymphoid cells (ILCs) are a group of lymphocytes that are devoid of antigen-specific
receptors and are mainly found in tissues. The subtypes ILC1, 2, and 3 mirror T-cell …