The evolution and adaptation of A-to-I RNA editing
AL Yablonovitch, P Deng, D Jacobson, JB Li - PLoS genetics, 2017 - journals.plos.org
Adenosine-to-inosine (A-to-I) RNA editing is an important post-transcriptional modification
that affects the information encoded from DNA to RNA to protein. RNA editing can generate …
that affects the information encoded from DNA to RNA to protein. RNA editing can generate …
[HTML][HTML] The many roles of A-to-I RNA editing in animals: functional or adaptive?
Metazoan adenosine-to-inosine (A-to-I) RNA editing is a highly conserved mechanism that
diversifies the transcriptome by post-transcriptionally converting adenosine to inosine …
diversifies the transcriptome by post-transcriptionally converting adenosine to inosine …
Experimental evidence for the functional importance and adaptive advantage of A-to-I RNA editing in fungi
K Xin, Y Zhang, L Fan, Z Qi, C Feng… - Proceedings of the …, 2023 - National Acad Sciences
Adenosine-to-inosine (A-to-I) editing is the most prevalent type of RNA editing in animals,
and it occurs in fungi specifically during sexual reproduction. However, it is debatable …
and it occurs in fungi specifically during sexual reproduction. However, it is debatable …
Adaptation of A-to-I RNA editing in bacteria, fungi, and animals
Y Duan, H Li, W Cai - Frontiers in Microbiology, 2023 - frontiersin.org
Adenosine-to-inosine (A-to-I) RNA editing is a prevalent type of RNA modification in all
domains of lives ranging from bacteria (Liao et al., 2023), fungi (Liu et al., 2017), to …
domains of lives ranging from bacteria (Liao et al., 2023), fungi (Liu et al., 2017), to …
Chloroplast C-to-U RNA editing in vascular plants is adaptive due to its restorative effect: testing the restorative hypothesis
Y Duan, W Cai, H Li - RNA, 2023 - rnajournal.cshlp.org
The adaptiveness of nonsynonymous RNA editing (recoding) could be conferred by the
flexibility of the temporal-spatially controllable proteomic diversity, or by its restorative effect …
flexibility of the temporal-spatially controllable proteomic diversity, or by its restorative effect …
Genome-wide analysis on driver and passenger RNA editing sites suggests an underestimation of adaptive signals in insects
Y Zhang, Y Duan - Genes, 2023 - mdpi.com
Adenosine-to-inosine (A-to-I) RNA editing leads to a similar effect to A-to-G mutations. RNA
editing provides a temporo-spatial flexibility for organisms. Nonsynonymous (Nonsyn) RNA …
editing provides a temporo-spatial flexibility for organisms. Nonsynonymous (Nonsyn) RNA …
The landscape of A-to-I RNA editome is shaped by both positive and purifying selection
The hydrolytic deamination of adenosine to inosine (A-to-I editing) in precursor mRNA
induces variable gene products at the post-transcription level. How and to what extent A-to-I …
induces variable gene products at the post-transcription level. How and to what extent A-to-I …
Identification and interpretation of A-to-I RNA editing events in insect transcriptomes
Adenosine-to-inosine (A-to-I) RNA editing is the most prevalent RNA modification in the
nervous systems of metazoans. To study the biological significance of RNA editing, we first …
nervous systems of metazoans. To study the biological significance of RNA editing, we first …
Evidence that alternative transcriptional initiation is largely nonadaptive
Alternative transcriptional initiation (ATI) refers to the frequent observation that one gene has
multiple transcription start sites (TSSs). Although this phenomenon is thought to be adaptive …
multiple transcription start sites (TSSs). Although this phenomenon is thought to be adaptive …
Adaptive proteome diversification by nonsynonymous A-to-I RNA editing in coleoid cephalopods
Y Shoshan, N Liscovitch-Brauer… - Molecular Biology …, 2021 - academic.oup.com
RNA editing by the ADAR enzymes converts selected adenosines into inosines, biological
mimics for guanosines. By doing so, it alters protein-coding sequences, resulting in novel …
mimics for guanosines. By doing so, it alters protein-coding sequences, resulting in novel …