[HTML][HTML] Helicobacter pylori virulence genes

A Šterbenc, E Jarc, M Poljak… - World journal of …, 2019 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is one of the most important human pathogens, infecting
approximately half of the global population. Despite its high prevalence, only a subset of H …

Virulence of Helicobacter pylori outer membrane proteins: an updated review

C Xu, DM Soyfoo, Y Wu, S Xu - European Journal of Clinical Microbiology …, 2020 - Springer
Helicobacter pylori (H. pylori) infection is associated with some gastric diseases, such as
gastritis, peptic ulcer, and gastric cancer. CagA and VacA are known virulence factors of H …

Human pathogens utilize host extracellular matrix proteins laminin and collagen for adhesion and invasion of the host

B Singh, C Fleury, F Jalalvand… - FEMS microbiology …, 2012 - academic.oup.com
Laminin (Ln) and collagen are multifunctional glycoproteins that play an important role in
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …

Helicobacter pylori diversity and gastric cancer risk

TL Cover - MBio, 2016 - Am Soc Microbiol
Gastric cancer is a leading cause of cancer-related death worldwide. Helicobacter pylori
infection is the strongest known risk factor for this malignancy. An important goal is to identify …

Virulence Factors of Helicobacter pylori: A Review

BM Roesler, EMA Rabelo-Gonçalves… - Clinical Medicine …, 2014 - journals.sagepub.com
Helicobacter pylori is a spiral-shaped Gram-negative bacterium that colonizes the human
stomach and can establish a long-term infection of the gastric mucosa, a condition that …

Helicobacter pylori Vacuolating Toxin and Gastric Cancer

MS McClain, AC Beckett, TL Cover - Toxins, 2017 - mdpi.com
Helicobacter pylori VacA is a channel-forming toxin unrelated to other known bacterial
toxins. Most H. pylori strains contain a vacA gene, but there is marked variation among …

The Role of Helicobacter pylori Outer Membrane Proteins in Adherence and Pathogenesis

M Oleastro, A Ménard - Biology, 2013 - mdpi.com
Helicobacter pylori is one of the most successful human pathogens, which colonizes the
mucus layer of the gastric epithelium of more than 50% of the world's population. This …

40 Years of Helicobacter pylori: A Revolution in Biomedical Thought

IA Charitos, D D'Agostino, S Topi, L Bottalico - Gastroenterology Insights, 2021 - mdpi.com
Background: Various microorganisms such as bacteria, virus, and fungi can infect humans
and cause not just a simple infection but septic conditions, organ dysfunction, and …

Adhesion and Invasion of Gastric Mucosa Epithelial Cells by Helicobacter pylori

Y Huang, Q Wang, D Cheng, W Xu… - Frontiers in cellular and …, 2016 - frontiersin.org
Helicobacter pylori is the main pathogenic bacterium involved in chronic gastritis and peptic
ulcer and a class 1 carcinogen in gastric cancer. Current research focuses on the …

A Tale of Two Toxins: Helicobacter Pylori CagA and VacA Modulate Host Pathways that Impact Disease

KR Jones, JM Whitmire, DS Merrell - Frontiers in microbiology, 2010 - frontiersin.org
Helicobacter pylori is a pathogenic bacterium that colonizes more than 50% of the world's
population, which leads to a tremendous medical burden. H. pylori infection is associated …