In vivo cerebral aneurysm models

JW Thompson, O Elwardany, DJ McCarthy… - Neurosurgical …, 2019 - thejns.org
Cerebral aneurysm rupture is a devastating event resulting in subarachnoid hemorrhage
and is associated with significant morbidity and death. Up to 50% of individuals do not …

[HTML][HTML] Current status and outlook of biodegradable metals in neuroscience and their potential applications as cerebral vascular stent materials

M Li, M Jiang, Y Gao, Y Zheng, Z Liu, C Zhou… - Bioactive Materials, 2022 - Elsevier
Over the past two decades, biodegradable metals (BMs) have emerged as promising
materials to fabricate temporary biomedical devices, with the purpose of avoiding potential …

Bioresorbable flow diverters for the treatment of intracranial aneurysms: review of current literature and future directions

AA Oliver, KD Carlson, C Bilgin, JLA Larco… - Journal of …, 2023 - jnis.bmj.com
The use of flow diverters is a rapidly growing endovascular approach for the treatment of
intracranial aneurysms. All FDA-approved flow diverters are composed of nitinol or cobalt …

[HTML][HTML] Neuroprotective effects of intraperitoneally injected Mg alloy extracts on middle cerebral artery occluded mouse with reperfusion injury

L Wang, Y Hu, H Zhang, M Jiang, Y Zhang… - Journal of Magnesium …, 2024 - Elsevier
Magnesium (Mg) alloy stents have been commercialized for the treatment of cardiovascular
diseases and extensively studied for possible implantation in major organs. However, the in …

[HTML][HTML] Neuroprotection on ischemic brain injury by Mg2+/H2 released from endovascular Mg implant

Y Zhang, H Zhang, M Jiang, X Cao, X Ge, B Song… - Bioactive Materials, 2024 - Elsevier
Most acute ischemic stroke patients with large vessel occlusion require stent implantation for
complete recanalization. Yet, due to ischemia-reperfusion injury, over half of these patients …

Benchtop proof of concept and comparison of iron-and magnesium-based bioresorbable flow diverters

AA Oliver, C Bilgin, AJ Vercnocke, KD Carlson… - Journal of …, 2022 - thejns.org
OBJECTIVE Bioresorbable flow diverters (BRFDs) could significantly improve the
performance of next-generation flow diverter technology. In the current work, magnesium …

Aneurysm wall cellularity affects healing after coil embolization: assessment in a rat saccular aneurysm model

E Nevzati, J Rey, D Coluccia, BE Grüter… - Journal of …, 2020 - jnis.bmj.com
Background and purpose Despite significant technical advances, recanalization rates after
endovascular therapy of ruptured intracranial aneurysms (IAs) remain a clinical challenge. A …

Parent artery-initiated and stent-mediated neointima formation in a rat saccular side wall model

S Wanderer, BE Grüter, G Boillat… - Journal of …, 2022 - jnis.bmj.com
Background Unlike clipping that forms an immediate barrier of blood flow into intracranial
aneurysms, endovascular treatments rely on thrombus organization and neointima …

Arterial pouch microsurgical bifurcation aneurysm model in the rabbit

S Wanderer, C Waltenspuel, BE Grüter… - JoVE (Journal of …, 2020 - jove.com
Endovascular treatment for intracranial aneurysms gained importance over the past
decades, consequently there is an increased need of testing endovascular devices. Animal …

Current status and outlook of potential applications of biodegradable materials in cerebral vascular stents

Y Xing, G Liang, T Zhu - Neurosurgical Review, 2022 - Springer
The treatment of intracranial aneurysms (IAs) has undergone a very significant
transformation in recent decades, and endovascular interventions have gradually become …