Cerebral radiation necrosis: incidence, pathogenesis, diagnostic challenges, and future opportunities

FS Ali, O Arevalo, S Zorofchian, A Patrizz… - Current oncology …, 2019 - Springer
Abstract Purpose of Review Cerebral radiation necrosis (CRN) is a major dose-limiting
adverse event of radiotherapy. The incidence rate of RN varies with the radiotherapy …

Treatment of radiation‐induced brain necrosis

X Yang, H Ren, J Fu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
Radiation‐induced brain necrosis (RBN) is a serious complication of intracranial as well as
skull base tumors after radiotherapy. In the past, due to the lack of effective treatment …

Decoding patient heterogeneity influencing radiation-induced brain necrosis

I Chamseddine, K Shah, H Lee, F Ehret… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: In radiotherapy (RT) for brain tumors, patient heterogeneity masks treatment
effects, complicating the prediction and mitigation of radiation-induced brain necrosis …

Radiation necrosis after radiation therapy treatment of brain metastases: A computational approach

B Ocaña-Tienda, O León-Triana… - PLOS Computational …, 2024 - journals.plos.org
Metastasis is the process through which cancer cells break away from a primary tumor,
travel through the blood or lymph system, and form new tumors in distant tissues. One of the …

Hibernation as a tool for radiation protection in space exploration

A Puspitasari, M Cerri, A Takahashi, Y Yoshida… - Life, 2021 - mdpi.com
With new and advanced technology, human exploration has reached outside of the Earth's
boundaries. There are plans for reaching Mars and the satellites of Jupiter and Saturn, and …

Does protracted radon exposure play a role in the development of dementia?

Y Zhang, L Lu, C Chen, RW Field, M D'Alton… - Environmental …, 2022 - Elsevier
Radon is a ubiquitous radioactive gas that decays into a series of solid radioactive decay
products. Radon, and its decay products, enter the human body primarily through inhalation …

X-ray irradiation induces disruption of the blood–brain barrier with localized changes in claudin-5 and activation of microglia in the mouse brain

Y Yoshida, Y Sejimo, M Kurachi, Y Ishizaki… - Neurochemistry …, 2018 - Elsevier
X-ray irradiation (X-irradiation) induces disruption of the blood–brain barrier (BBB).
However, the mechanisms underlying the permeability changes are unclear. Therefore, in …

Stem-cell therapy as a potential strategy for radiation-induced brain injury

C Chu, Y Gao, X Lan, J Lin, AM Thomas… - Stem Cell Reviews and …, 2020 - Springer
Radiation therapy is a standard and effective non-surgical treatment for primary brain tumors
and metastases. However, this strategy inevitably results in damage of normal brain tissue …

Radiosurgery for Brain Metastases: Challenges in Imaging Interpretation after Treatment

A Romano, G Moltoni, A Blandino, S Palizzi, A Romano… - Cancers, 2023 - mdpi.com
Simple Summary Stereotactic radiosurgery is one of the main treatments for patients with
brain metastases, with important achievements in terms of patient prognosis. Nevertheless …

Risk of radiation necrosis after stereotactic radiosurgery for melanoma brain metastasis by anatomical location

S Choi, A Hong, T Wang, S Lo, B Chen, I Silva… - Strahlentherapie und …, 2021 - Springer
Purpose In this retrospective study, we have explored the anatomical factors that lead to the
development of radiation necrosis (RN) in the setting of stereotactic radiosurgery (SRS) for …