Maternal obesity: new placental paradigms unfolded

C Brombach, W Tong, DA Giussani - Trends in molecular medicine, 2022 - cell.com
The prevalence of maternal obesity is increasing at an alarming rate, and is providing a
major challenge for obstetric practice. Adverse effects on maternal and fetal health are …

Effects of maternal obesity on placental phenotype

AL Fowden, EJ Camm… - Current Vascular …, 2021 - ingentaconnect.com
The incidence of obesity is rising rapidly worldwide with the consequence that more women
are entering pregnancy overweight or obese. This leads to an increased incidence of clinical …

Obesity and diet independently affect maternal immunity, maternal gut microbiota and pregnancy outcome in mice

L Wekema, S Schoenmakers, N Schenkelaars… - Frontiers in …, 2024 - frontiersin.org
Introduction Maternal obesity poses risks for both mother and offspring during pregnancy,
with underlying mechanisms remaining largely unexplored. Obesity is associated with …

Exercise prevents the adverse effects of maternal obesity on placental vascularization and fetal growth

JS Son, X Liu, Q Tian, L Zhao, Y Chen… - The Journal of …, 2019 - Wiley Online Library
Key points Maternal exercise improves the metabolic health of maternal mice challenged
with a high‐fat diet. Exercise intervention of obese mothers prevents fetal overgrowth …

Diabetic pregnancy and maternal high-fat diet impair mitochondrial dynamism in the developing fetal rat heart by sex-specific mechanisms

TD Larsen, KH Sabey, AJ Knutson, TCT Gandy… - International journal of …, 2019 - mdpi.com
Infants born to diabetic or obese mothers are at greater risk of heart disease at birth and
throughout life, but prevention is hindered because underlying mechanisms remain poorly …

Mitochondrial transfer improves cardiomyocyte bioenergetics and viability in male rats exposed to pregestational diabetes

EJ Louwagie, TD Larsen, AL Wachal… - International journal of …, 2021 - mdpi.com
Offspring born to diabetic or obese mothers have a higher lifetime risk of heart disease.
Previously, we found that rat offspring exposed to late-gestational diabetes mellitus (LGDM) …

Rodent models in placental research. Implications for fetal origins of adult disease

N Aguilera, F Salas-Pérez, M Ortíz, D Álvarez… - Animal …, 2022 - SciELO Brasil
Rodent models in rats, mice, and guinea pigs have been extremely helpful to gain insight
into pregnancy physiology and pathologies-related. Moreover, they have allowed …

[HTML][HTML] Fructooligosaccharide ameliorates high-fat induced intrauterine inflammation and improves lipid profile in the hamster offspring

S Mohammed, SSY Qadri, IA Mir, NB Kondapalli… - The Journal of …, 2022 - Elsevier
Maternal high-fat diet (HFD) often results in intrauterine and feto-placental inflammation, and
increases the risks of fetal programming of metabolic diseases. Intake of prebiotic is reported …

[HTML][HTML] A high docosahexaenoic acid diet alters lung inflammation and recovery following repetitive exposure to aqueous organic dust extracts

A Ulu, A Burr, AJ Heires, J Pavlik, T Larsen… - The Journal of nutritional …, 2021 - Elsevier
Agricultural workers, especially those who work in swine confinement facilities, are at
increased risk for developing pulmonary diseases including asthma, chronic obstructive …

Maternal n-3 PUFA deficiency alters uterine artery remodeling and placental epigenome in the mice

V Srinivas, A Molangiri, A Mallepogu, SR Kona… - The Journal of nutritional …, 2021 - Elsevier
The maternal n-3 polyunsaturated fatty acid (PUFA) deficiency on decidual vascular
structure and angiogenesis in mice placenta was investigated. Namely, we studied uterine …