State of the art in epitope mapping and opportunities in COVID-19

SM Hamed, MM Sakr, GS El-Housseiny, R Wasfi… - Future Science …, 2023 - Taylor & Francis
The understanding of any disease calls for studying specific biological structures called
epitopes. One important tool recently drawing attention and improving efficiency in both …

[HTML][HTML] Pandemic strategies with computational and structural biology against COVID-19: a retrospective

CH Liu, CH Lu, LT Lin - Computational and Structural Biotechnology …, 2022 - Elsevier
The emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),
which is the etiologic agent of the coronavirus disease 2019 (COVID-19) pandemic, has …

The potential application of artificial intelligence in veterinary clinical practice and biomedical research

OC Akinsulie, I Idris, VA Aliyu, S Shahzad… - Frontiers in Veterinary …, 2024 - frontiersin.org
Artificial intelligence (AI) is a fast-paced technological advancement in terms of its
application to various fields of science and technology. In particular, AI has the potential to …

Leveraging artificial intelligence in vaccine development: A narrative review

DB Olawade, J Teke, O Fapohunda… - Journal of …, 2024 - Elsevier
Vaccine development stands as a cornerstone of public health efforts, pivotal in curbing
infectious diseases and reducing global morbidity and mortality. However, traditional …

Vaccine design and development: Exploring the interface with computational biology and AI

Ananya, DC Panchariya, A Karthic… - International Reviews …, 2024 - Taylor & Francis
Computational biology involves applying computer science and informatics techniques in
biology to understand complex biological data. It allows us to collect, connect, and analyze …

[HTML][HTML] Creating an Innovative Artificial Intelligence–Based Technology (TCRact) for Designing and Optimizing T Cell Receptors for Use in Cancer Immunotherapies …

J Bujak, S Kłęk, M Balawejder… - JMIR Research …, 2023 - researchprotocols.org
Background: Cancer continues to be the leading cause of mortality in high-income countries,
necessitating the development of more precise and effective treatment modalities …

Proteomics analysis of methionine enkephalin upregulated macrophages against infection by the influenza-A virus

W Fu, Z Xie, M Bai, Z Zhang, Y Zhao, J Tian - Proteome Science, 2023 - Springer
Macrophages have a vital role in phagocytosis and antiviral effect against invading influenza
viruses. Previously, we found that methionine enkephalin (MENK) inhibited influenza virus …

ARDitox: platform for the prediction of TCRs potential off-target binding

VM Pienkowski, T Boschert, P Skoczylas… - bioRxiv, 2023 - biorxiv.org
Cellular immunotherapies, such as those utilizing T lymphocytes expressing native or
engineered T cell receptors (TCRs), have already demonstrated therapeutic efficacy …

Artificial Intelligence: Current and Future Role in Veterinary and Public Medicine

MM Amer, AM Amer - Egyptian Journal of Veterinary Sciences, 2024 - journals.ekb.eg
Artificial intelligence (AI) is revolutionizing many industries and medicine. This paper
provides an overview of AI's current and future role in medicine. Currently, AI is used in …

Transgenic T cell therapy targeting the glioblastoma stem cell antigen PTPRZ1 with a vaccine-induced, patient-derived T cell receptor

L Bunse, YC Chih, AC Dietsch, P Koopmann, X Ma… - 2024 - researchsquare.com
Response to CAR-T cell therapy in glioblastoma (GB) patients is limited, particularly
because of the paucity of cell surface immunotherapeutic targets or low antigen sensitivity …