Food-derived bioactive peptides in human health: Challenges and opportunities

S Chakrabarti, S Guha, K Majumder - Nutrients, 2018 - mdpi.com
Recent scientific evidence suggests that food proteins not only serve as nutrients, but can
also modulate the body's physiological functions. These physiological functions are primarily …

Chloroplast genomes: diversity, evolution, and applications in genetic engineering

H Daniell, CS Lin, M Yu, WJ Chang - Genome biology, 2016 - Springer
Chloroplasts play a crucial role in sustaining life on earth. The availability of over 800
sequenced chloroplast genomes from a variety of land plants has enhanced our …

Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

F Pistollato, S Sumalla Cano, I Elio… - Nutrition …, 2016 - academic.oup.com
It has been hypothesized that alterations in the composition of the gut microbiota might be
associated with the onset of certain human pathologies, such as Alzheimer disease, a …

[HTML][HTML] Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

P Lundquist, P Artursson - Advanced drug delivery reviews, 2016 - Elsevier
In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …

Cholera toxin subunit B as adjuvant––an accelerator in protective immunity and a break in autoimmunity

T Stratmann - Vaccines, 2015 - mdpi.com
Cholera toxin subunit B (CTB) is the nontoxic portion of cholera toxin. Its affinity to the
monosialotetrahexosylganglioside (GM1) that is broadly distributed in a variety of cell types …

The engineered chloroplast genome just got smarter

S Jin, H Daniell - Trends in plant science, 2015 - cell.com
Chloroplasts are known to sustain life on earth by providing food, fuel, and oxygen through
the process of photosynthesis. However, the chloroplast genome has also been smartly …

Plant molecular pharming for the treatment of chronic and infectious diseases

E Stoger, R Fischer, M Moloney… - Annual review of plant …, 2014 - annualreviews.org
Plant molecular pharming has emerged as a niche technology for the manufacture of
pharmaceutical products indicated for chronic and infectious diseases, particularly for …

Plant‐made oral vaccines against human infectious diseases—are we there yet?

HT Chan, H Daniell - Plant biotechnology journal, 2015 - Wiley Online Library
Although the plant‐made vaccine field started three decades ago with the promise of
developing low‐cost vaccines to prevent infectious disease outbreaks and epidemics …

Engineered chloroplast dsRNA silences cytochrome p450 monooxygenase, V‐ATPase and chitin synthase genes in the insect gut and disrupts Helicoverpa armigera …

S Jin, ND Singh, L Li, X Zhang… - Plant biotechnology …, 2015 - Wiley Online Library
In the past two decades, chloroplast genetic engineering has been advanced to achieve
high‐level protein accumulation but not for down‐regulation of targeted genes. Therefore, in …

Oral delivery of Angiotensin-converting enzyme 2 and Angiotensin-(1-7) bioencapsulated in plant cells attenuates pulmonary hypertension

V Shenoy, KC Kwon, A Rathinasabapathy, S Lin… - …, 2014 - Am Heart Assoc
Emerging evidences indicate that diminished activity of the vasoprotective axis of the renin–
angiotensin system, constituting angiotensin-converting enzyme 2 (ACE2) and its enzymatic …