Osteoporosis is called a silent disease, because it is difficult to detect until comprehensive
examinations for osteoporosis are performed or osteoporotic fractures occur. Zoledronic acid …

Phospholipase C (PLC) is an essential mediator of cellular signaling. PLC regulates multiple
cellular processes by generating bioactive molecules such as inositol-1, 4, 5-triphosphate …

Osteoblasts and osteoclasts participate in the process of bone remodelling to meet the
needs of normal growth and development or repair pathological damage. Endoplasmic …

Bones serve mechanical and defensive functions, as well as regulating the balance of
calcium ions and housing bone marrow.. The qualities of bones do not remain constant …

Cancers have been considered as one of the most severe health problems in the world.
Efforts to elucidate the cancer progression reveal the importance of bone metastasis for …

Hepatocellular carcinoma (HCC) is largely associated with aberrant activation of Wnt/β‐
catenin signaling. Nevertheless, how membrane lipid composition is altered in HCC cells …

As key regulators, long non‐coding RNAs (lncRNAs) play a crucial role in the ruminant
mammary gland. However, the function of lncRNAs in milk fat synthesis from dairy cows is …

The maintenance of bone is dependent on both osteoclasts, which break down bone, and
osteoblasts, which build new bone. Various bone-related disorders, including osteoporosis …

Atherosclerosis (AS) is the primary cause of various cardiovascular and cerebrovascular
diseases and has high morbidity and mortality rates. Oxidative stress‑induced endothelial …

Background & aims Leucine-rich repeat G-protein-coupled receptor 4 (LGR4) and its ligands
R-spondin1-4 (Rspos) have been vastly investigated in embryonic development. The …