Biological modulation of renal ischemia–reperfusion injury

MGJ Snoeijs, LWE van Heurn… - Current opinion in organ …, 2010 - journals.lww.com
We conclude that the pathophysiology of delayed graft function after kidney transplantation
is complex and shares broad similarity with rodent models of ischemic acute kidney injury …

[HTML][HTML] Results of an explorative clinical evaluation suggest immediate and persistent post-reperfusion metabolic paralysis drives kidney ischemia reperfusion injury

JH Lindeman, LG Wijermars, S Kostidis… - Kidney International, 2020 - Elsevier
Delayed graft function is the manifestation of ischemia reperfusion injury in the context of
kidney transplantation. While hundreds of interventions successfully reduce ischemia …

Ex vivo normothermic machine perfusion is safe, simple, and reliable: results from a large animal model

A Nassar, Q Liu, K Farias, G D'Amico… - Surgical …, 2015 - journals.sagepub.com
Introduction. Normothermic machine perfusion (NMP) is an emerging preservation modality
that holds the potential to prevent the injury associated with low temperature and to promote …

[HTML][HTML] Intraoperative portal vein blood flow predicts allograft and patient survival following liver transplantation

AL Spitzer, AAS Dick, R Bakthavatsalam… - Hpb, 2010 - Elsevier
Background We hypothesized that operative variables might predict survival following liver
transplantation. Methods We examined perioperative variables from 469 liver transplants …

Transplantation of cold stored porcine kidneys after controlled oxygenated rewarming

A Gallinat, J Lu, C von Horn, M Kaths… - Artificial …, 2018 - Wiley Online Library
The concept of “controlled oxygenated rewarming”(COR) using ex vivo machine perfusion
after cold storage was evaluated as tool to improve renal graft function after transplantation …

[HTML][HTML] Left renal vein ligation: a technique to mitigate low portal flow from splenic vein siphon during liver transplantation

RR Slater, N Jabbour, A Abou Abbass, V Patil… - American Journal of …, 2011 - Elsevier
Low portal vein flows in liver transplant have been associated with poor allograft survival.
Identifying and ameliorating causes of inadequate portal flow is paramount. We describe …

Effects of propofol and sevoflurane on hepatic blood flow: a randomized controlled trial

J Van Limmen, P Wyffels, F Berrevoet, A Vanlander… - BMC …, 2020 - Springer
Background Maintaining adequate perioperative hepatic blood flow (HBF) supply is
essential for preservation of postoperative normal liver function. Propofol and sevoflurane …

Improved preservation and microcirculation with POLYSOL after transplantation in a porcine kidney autotransplantation model

MCJM Schreinemachers, BM Doorschodt… - Nephrology Dialysis …, 2009 - academic.oup.com
Background. The most widely used preservation method for kidney grafts is cold static
storage (CS) using the University of Wisconsin (UW) solution. To date, new preservation …

An integrated machine learning model enhances delayed graft function prediction in pediatric renal transplantation from deceased donors

XY Liu, RT Feng, WX Feng, WW Jiang, JA Chen… - BMC medicine, 2024 - Springer
Background Kidney transplantation is the optimal renal replacement therapy for children
with end-stage renal disease; however, delayed graft function (DGF), a common post …

[PDF][PDF] Arterial blood flow predicts graft survival in liver transplant patients

S Pratschke, G Meimarakis, S Mayr, C Graeb… - Liver …, 2011 - Wiley Online Library
Proper liver perfusion is essential for sufficient organ function after liver transplantation. The
aim of this study was to determine the effects of portal and arterial blood flow on liver …