Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from
a binding site with unknown function to a firmly established major effector within the …

The renin–angiotensin system (RAS) was initially considered to be part of the endocrine
system regulating water and electrolyte balance, systemic vascular resistance, blood …

The renin-angiotensin-aldosterone system (RAAS) is a critical regulator of blood volume,
electrolyte balance, and systemic vascular resistance. While the baroreceptor reflex …

Prolactin is a protein hormone of the anterior pituitary gland that was originally named for its
ability to promote lactation in response to the suckling stimulus of hungry young mammals …

Since the first identification of renin by Tigerstedt and Bergmann in 1898, the renin-
angiotensin system (RAS) has been extensively studied. The current view of the system is …

THERE are two major angiotensin II receptor isoforms, AT1 and AT2. AT1 mediates the well-
known pressor and mitogenic effects of angiotensin II (refs 1-5), but the signalling …

Angiotensin II receptor blockers (ARBs, collectively called sartans) are widely used
compounds therapeutically effective in cardiovascular disorders, renal disease, the …

The renin-angiotensin system is a major physiological regulator of body fluid volume,
electrolyte balance, and arterial pressure. Virtually all of the biological actions of the …

Angiotensin II (ANG II) is known to be a potent growth promoting factor for vascular smooth
muscle cells and fibroblasts but little is known about its influence on growth in endothelial …

There are two major isoforms of the angiotensin II receptor, type 1 (AT1) and type 2 (AT2).
AT2 is distinguished from AT1 with respect to its ligand selectivity, its insensitivity to non …