Phenotypic heterogeneity has been observed in most malignancies, which represents a
considerable challenge for tumor therapy. In recent decades, the biological function and …

Human leukocyte antigen G (HLA-G) is a nonclassic major histocompatibility complex
(MHC) class I molecule that functions as an immunomodulatory molecule capable of …

Over the past few years, HLA-G, the non-classical HLA class I molecule, has been the center
of investigations that have led to the description of its specific structural and functional …

The immunological relationship between the mother and the fetus is a bi-directional
communication determined on the one hand by fetal antigen presentation and on the other …

Human leukocyte antigen-G (HLA-G) is a nonclassical HLA class-I molecule that was found
to be expressed by placental trophoblast cells 20 years ago. Because trophoblast forms the …

Maternal immune tolerance of the fetus is indispensable for a healthy pregnancy outcome.
Nowhere is this immune tolerance more important than at the fetal–maternal interface–the …

HLA-G molecule plays an important role on immune response regulation and has been
implicated on the inhibition of T and natural killer cell cytolytic function and inhibition of …

Human leukocyte antigen (HLA)-G molecule, a non-classical HLA-Ib molecule, is less
polymorphic when compared to classical HLA class I molecules. Human leukocyte antigen …

Human leucocyte antigen (HLA)‐G is expressed on trophoblast cells during pregnancy,
suggesting a role in protection of the semiallogeneic fetus. Published data suggest that HLA …

HLA-G is known to modulate the immune system activity in tissues where physiological
immune-tolerance is necessary (ie, maternal-fetal interface, thymus, and cornea). However …