Systematic review of herbs and dietary supplements for glycemic control in diabetes

GY Yeh, DM Eisenberg, TJ Kaptchuk… - Diabetes …, 2003 - Am Diabetes Assoc
OBJECTIVE—To conduct a systematic review of the published literature on the efficacy and
safety of herbal therapies and vitamin/mineral supplements for glucose control in patients …

Role of carnitine and its derivatives in the development and management of type 2 diabetes

J Bene, K Hadzsiev, B Melegh - Nutrition & diabetes, 2018 - nature.com
Type 2 diabetes is a highly prevalent chronic metabolic disorder characterized by
hyperglycemia and associated with several complications such as retinopathy …

Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility

DM Muoio, RC Noland, JP Kovalik, SE Seiler… - Cell metabolism, 2012 - cell.com
The concept of" metabolic inflexibility" was first introduced to describe the failure of insulin-
resistant human subjects to appropriately adjust mitochondrial fuel selection in response to …

[HTML][HTML] Oxidative stress: New insights on the association of non-alcoholic fatty liver disease and atherosclerosis

L Polimeni, M Del Ben, F Baratta, L Perri… - World journal of …, 2015 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging
chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from …

Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control

RC Noland, TR Koves, SE Seiler, H Lum… - Journal of biological …, 2009 - ASBMB
In addition to its essential role in permitting mitochondrial import and oxidation of long chain
fatty acids, carnitine also functions as an acyl group acceptor that facilitates mitochondrial …

Antioxidants in the treatment of diabetes

S Golbidi, S Alireza Ebadi, I Laher - Current diabetes reviews, 2011 - ingentaconnect.com
Diabetes is a chronic metabolic disorder that continues to present as a major health problem
worldwide. It is characterized by absolute or relative deficiencies in insulin secretion and/or …

Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L-carnitine

SM Marcovina, C Sirtori, A Peracino… - Translational …, 2013 - Elsevier
Mitochondria play important roles in human physiological processes, and therefore, their
dysfunction can lead to a constellation of metabolic and nonmetabolic abnormalities such as …

Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine …

R Ringseis, J Keller, K Eder - European journal of nutrition, 2012 - Springer
Background Although carnitine is best known for its role in the import of long-chain fatty
acids (acyl groups) into the mitochondrial matrix for subsequent β-oxidation, carnitine is also …

L-carnitine improves glucose disposal in type 2 diabetic patients

G Mingrone, AV Greco, E Capristo… - Journal of the …, 1999 - Taylor & Francis
Objective: Aim of the present study is to evaluate the effects of L-carnitine on insulin-
mediated glucose uptake and oxidation in type II diabetic patients and compare the results …

Expression of Concern: Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double …

M Samimi, M Jamilian, FA Ebrahimi… - Clinical …, 2016 - Wiley Online Library
Objective Limited data are available for evaluating the effects of oral carnitine
supplementation on weight loss and metabolic profiles of women with polycystic ovary …