[HTML][HTML] Pulmonary large-cell neuroendocrine carcinoma: from epidemiology to therapy

M Fasano, CM Della Corte, F Papaccio… - Journal of Thoracic …, 2015 - Elsevier
Lung neuroendocrine tumors are a heterogeneous subtype of pulmonary cancers
representing approximately 20% of all lung cancers, including small-cell lung cancer …

Large cell neuroendocrine carcinoma of the lung: current understanding and challenges

E Andrini, PV Marchese, D De Biase… - Journal of Clinical …, 2022 - mdpi.com
Large cell neuroendocrine carcinoma of the lung (LCNEC) is a rare and highly aggressive
type of lung cancer, with a complex biology that shares similarities with both small-cell lung …

Large cell neuroendocrine carcinoma of the lung: clinico-pathologic features, treatment, and outcomes

J Naidoo, ML Santos-Zabala, T Iyriboz, KM Woo… - Clinical lung cancer, 2016 - Elsevier
Background Large cell neuroendocrine carcinoma (LCNEC) accounts for approximately 3%
of lung cancers. Pathologic classification and optimal therapies are debated. We report the …

Chemotherapy for pulmonary large cell neuroendocrine carcinoma: similar to that for small cell lung cancer or non-small cell lung cancer?

JM Sun, MJ Ahn, JS Ahn, SW Um, H Kim, HK Kim… - Lung Cancer, 2012 - Elsevier
BACKGROUND: There is controversy regarding palliative chemotherapy for large cell
neuroendocrine carcinoma (LCNEC). We evaluated whether advanced LCNEC should be …

Management of large cell neuroendocrine carcinoma

V Corbett, S Arnold, L Anthony, A Chauhan - Frontiers in oncology, 2021 - frontiersin.org
Background Large cell neuroendocrine carcinoma (LCNEC) is a rare, aggressive cancer
with a dismal prognosis. The majority of cases occur in the lung and the gastrointestinal …

Identification of microRNAs differentially expressed between lung squamous cell carcinoma and lung adenocarcinoma

J Hamamoto, K Soejima, S Yoda… - Molecular …, 2013 - spandidos-publications.com
Recent advances in the treatment of non-small cell lung cancer (NSCLC) with new agents
require accurate histological subtyping at diagnosis to avoid the higher risk of an adverse …

Treatment options for patients with large cell neuroendocrine carcinoma of the lung

A Iyoda, T Makino, S Koezuka, H Otsuka… - General Thoracic and …, 2014 - Springer
Large cell neuroendocrine carcinoma (LCNEC) of the lung is categorized as a variant of
large cell carcinomas, and LCNEC tumors display biological behaviors resembling those of …

Treatment of lung large cell neuroendocrine carcinoma

G Lo Russo, S Pusceddu, C Proto, M Macerelli… - Tumor Biology, 2016 - Springer
Lung large cell neuroendocrine carcinoma (L-LCNEC) is a rare, aggressive, and difficult-to-
treat tumor. It is classified as a neuroendocrine subtype of large cell lung carcinoma (LCLC) …

Pulmonary large cell neuroendocrine carcinoma (LCNEC): a population-based study addressing recent molecular-genetic advances and emerging therapeutic …

J Khan, AQK Yasinzai, S Matosz, M Khan… - Clinical and …, 2023 - Springer
Background Large cell neuroendocrine carcinoma (LCNEC) of the lung is a rare, aggressive
cancer most commonly found in the lungs but not exclusively, with a worse prognosis than …

Treatment of pulmonary neuroendocrine tumours: state of the art and future developments

C Gridelli, A Rossi, G Airoma, R Bianco… - Cancer treatment …, 2013 - Elsevier
The current classification of pulmonary neuroendocrine tumours includes four subtypes: low-
grade typical carcinoid tumour (TC), intermediate-grade atypical carcinoid tumour (AC), and …