Alternative sampling devices to collect dried blood microsamples: state-of-the-art

L Delahaye, H Veenhof, BCP Koch… - Therapeutic drug …, 2021 - journals.lww.com
Dried blood spots (DBS) have been used in newborn screening programs for several years.
More recently, there has been growing interest in using DBS as a home sampling tool for the …

Biological fluid microsampling for therapeutic drug monitoring: A narrative review

A Cafaro, M Conti, F Pigliasco, S Barco, R Bandettini… - Biomedicines, 2023 - mdpi.com
Therapeutic drug monitoring (TDM) is a specialized area of laboratory medicine which
involves the measurement of drug concentrations in biological fluids with the aim of …

Controlling pre-analytical process in human serum/plasma metabolomics

D Chen, S Zhao, L Li, L Li - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Metabolome analysis is a key component of serum/plasma metabolomics studies for clinical
and biological applications. There are several steps involved, including pre-analytical …

Liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring of immunosuppressants and creatinine from a single dried blood spot using the …

S Deprez, K Van Uytfanghe, CP Stove - Analytica Chimica Acta, 2023 - Elsevier
In recent years, a lot of attention has been given to a more patient-centric therapeutic drug
monitoring (TDM) of immunosuppressant drugs (tacrolimus, sirolimus, everolimus and …

Microsampling tools for collecting, processing, and storing blood at the point‐of‐care

KR Baillargeon, CR Mace - Bioengineering & Translational …, 2023 - Wiley Online Library
In the wake of the COVID‐19 global pandemic, self‐administered microsampling tools have
reemerged as an effective means to maintain routine healthcare assessments without …

Revolutionizing blood Collection: innovations, applications, and the potential of Microsampling Technologies for monitoring metabolites and lipids

E Bossi, E Limo, L Pagani, N Monza, S Serrao, V Denti… - Metabolites, 2024 - mdpi.com
Blood serves as the primary global biological matrix for health surveillance, disease
diagnosis, and response to drug treatment, holding significant promise for personalized …

Multi-omics analysis from archival neonatal dried blood spots: limitations and opportunities

YJ Zhuang, Y Mangwiro, M Wake, R Saffery… - Clinical Chemistry and …, 2022 - degruyter.com
Newborn screening (NBS) programs operate in many countries, processing millions of dried
bloodspot (DBS) samples annually. In addition to early identification of various adverse …

Leveraging patient‐centric sampling for clinical drug development and decentralized clinical trials: promise to reality

KF Maass, MD Barfield, M Ito, CA James… - Clinical and …, 2022 - Wiley Online Library
Advances in the technologies to enable patient‐centric sampling (PCS) have the potential to
improve blood sample collection by enabling clinical trial participants to collect samples via …

Barriers and opportunities for the clinical implementation of therapeutic drug monitoring in oncology

BD Menz, SL Stocker, N Verougstraete… - British Journal of …, 2021 - Wiley Online Library
There are few fields of medicine in which the individualisation of medicines is more
important than in the area of oncology. Under‐dosing can have significant ramifications due …

[HTML][HTML] Hematocrit and standardization in DBS analysis: a practical approach for hormones mainly present in the plasma fraction

MT Ackermans, V de Kleijne, F Martens… - Clinica Chimica Acta, 2021 - Elsevier
Background and aim Dried blood spot (DBS) sampling has many advantages over
conventionally used blood samples, but is thought to suffer from hematocrit related issues …