[HTML][HTML] The risk of keratinocyte cancer in vitiligo and the potential mechanisms involved

A Rooker, W Ouwerkerk, MW Bekkenk… - Journal of Investigative …, 2024 - Elsevier
Although light skin types are associated with increased skin cancer risk, a lower incidence of
both melanoma and nonmelanoma skin cancer (NMSC) has been reported in patients with …

The IFN‐γ‐CXCL9/CXCL10‐CXCR3 axis in vitiligo: Pathological mechanism and treatment

H Liu, Y Wang, Q Le, J Tong… - European Journal of …, 2024 - Wiley Online Library
Vitiligo is a disease featuring distinct white patches that result from melanocyte destruction.
The overall pathogenesis of vitiligo remains to be elucidated. Nevertheless, considerable …

Predominant role of innate pro-inflammatory cytokines in vitiligo disease

N Gholijani, MR Yazdani, L Dastgheib - Archives of dermatological …, 2020 - Springer
Vitiligo is a skin disorder with melanocyte destruction and an autoimmune basis. Given the
importance of cytokines in autoimmunity, we aimed to find the cytokine profile of innate and …

The skin delivery of tofacitinib citrate using transethosomes and hybridized ethosomes/nanostructured lipid carriers for vitiligo therapy: Dermatopharmacokinetics and …

H Hesham, M Rady, RM Hathout, M Abdel-Halim… - International Journal of …, 2022 - Elsevier
Vitiligo is an autoimmune disease where its current treatment strategies are lengthy in
course and do not guarantee complete cure. Tofacitinib citrate (JAK inhibitor) is a potential …

Case series: gene expression analysis in canine Vogt-Koyanagi-Harada/uveodermatologic syndrome and vitiligo reveals conserved immunopathogenesis pathways …

IA Egbeto, CJ Garelli, C Piedra-Mora… - Frontiers in …, 2020 - frontiersin.org
Vogt-Koyanagi-Harada syndrome (VKH) and vitiligo are autoimmune diseases that target
melanocytes. VKH affects several organs such as the skin, hair follicle, eyes, ears, and …

The role of cytokines and vitamin D in vitiligo pathogenesis

AM Beyzaee, M Goldust, A Patil… - Journal of Cosmetic …, 2022 - Wiley Online Library
Vitiligo is a pigment‐related disease with a global prevalence of 0.2% to 1.8% associated
with considerable burden on quality of life. The treatment is still a challenge because of …

The IFNG rs1861494 Single Nucleotide Polymorphism Is Associated with Protection against Tuberculosis Disease in Argentina

A Rolandelli, JM Pellegrini, NO Amiano, MC Santilli… - Genes, 2018 - mdpi.com
Interferon gamma (IFNG) plays a key role during Mycobacterium tuberculosis (Mtb) infection,
and several polymorphisms located in its gene are associated with risk of tuberculosis in …

Association of single nucleotide polymorphisms of interferon-γ with pulmonary tuberculosis in population of Himachal Pradesh, India

NS Dhiman, V Saini, V Kumar - Gene, 2022 - Elsevier
Abstract Interferon-gamma (IFN-γ) plays an integral role in the host immunity against
tuberculosis (TB). The gene encoding IFN-γ is polymorphic and several studies have …

[HTML][HTML] The role of MicroRNAs in vitiligo: Regulators and therapeutic targets

L Li - Annals of Dermatology, 2020 - ncbi.nlm.nih.gov
Vitiligo is an acquired skin disorder clinically characterized by the progressive appearance
of white maculae due to a loss of functioning epidermal melanocytes. Studies have shown …

Polymorphisms and haplotypes of IL2RA, IL10, IFNG, IRF5, and CCR2 are associated with Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis in …

N Tang, J Huang, C Chen, X Wu, H Xu… - Pediatric Blood & …, 2021 - Wiley Online Library
Objective Cytokine storms are central to the development of Epstein–Barr virus‐associated
hemophagocytic lymphohistiocytosis (EBV‐HLH). Previous studies have shown that single …