In this brief review and perspective, we address the question of whether the immune
responses that bring about immune control of acute HIV infection are the same as, or distinct …

Elite controllers are a heterogeneous group of people living with HIV who control viral
replication without antiretroviral therapy. There is substantial evidence that at least some …

Interactions of killer cell immunoglobin-like receptors (KIR) with human leukocyte antigens
(HLA) class I regulate effector functions of key cytotoxic cells of innate and adaptive …

Driven by co‐evolution with pathogens, host immunity continuously adapts to optimize
defence against pathogens within a given environment. Recent advances in genetics …

Rare individuals, termed HIV controllers, spontaneously control HIV infection by mounting
efficient T cell responses against the virus. Protective CD4+ T cell responses from HIV …

Killer immunoglobulin-like receptors (KIR) regulate the function of natural killer cells through
interactions with various ligands on the surface of cells, thereby determining whether natural …

NK cells play a pivotal role in viral immunity, utilizing a large array of activating and inhibitory
receptors to identify and eliminate virus-infected cells. Killer-cell immunoglobulin-like …

Killer cell immunoglobulin-like receptors (KIRs) are expressed predominantly on natural
killer cells, where they play a key role in the regulation of innate immune responses. Recent …

Natural killer (NK) cells are essential for the elimination of the transformed and cancerous
cells. Killer cell immunoglobulin-like receptors (KIRs) which expressed by T and NK cells …

Natural Killer (NK) cells contribute to HIV control in adults, but HLA-B-mediated T-cell activity
has a more substantial impact on disease outcome. However, the HLA-B molecules …