Parkinson's disease (PD) is characterized by the loss of neuronal cells, which leads to
synaptic dysfunction and cognitive defects. Despite the advancements in treatment …

Ion mobility spectrometry (IMS) is a rapid separation technique that has experienced
exponential growth as a field of study. Interfacing IMS with mass spectrometry (IMS-MS) …

Abstract We present Mass Spectrometry-Data Independent Analysis software version 4 (MS-
DIAL 4), a comprehensive lipidome atlas with retention time, collision cross-section and …

The metabolome includes not just known but also unknown metabolites; however,
metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility …

The annotation of small molecules remains a major challenge in untargeted mass
spectrometry-based metabolomics. We here critically discuss structured elucidation …

Lipids are amongst the most important organic compounds in living organisms, where they
serve as building blocks for cellular membranes as well as energy storage and signaling …

Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

A comprehensive characterization of the lipidome from limited starting material remains very
challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid …

Mass spectrometry-based biomolecular analyses have become permanent fixtures of
academic, industrial, and clinical research settings. The rise in utilization of mass …

Ion mobility mass spectrometry (IM-MS) expands the analyte coverage of existing multi-omic
workflows by providing an additional separation dimension as well as a parameter for …