Acute myeloid leukemia (AML) is a malignant tumor of the immature myeloid hematopoietic
cells in the bone marrow (BM). It is a highly heterogeneous disease, with rising morbidity …

Abstract microRNAs (miRNAs) are important modulators of development. Owing to their
ability to simultaneously silence hundreds of target genes, they have key roles in large-scale …

Soon after its discovery, microRNA-9 (miR-9) attracted the attention of neurobiologists, since
it is one of the most highly expressed microRNAs in the developing and adult vertebrate …

Acute myeloid leukemia (AML) is a deadly hematologic malignancy characterized by the
uncontrolled growth of immature myeloid cells. Over the past several decades, we have …

Hematologic malignancies are one of the most common cancers, and the incidence has
been rising in recent decades. The clinical and molecular features of hematologic …

The cyclic AMP response element binding (CREB) protein has pleiotropic activities in
physiologic processes. Due to its central position downstream of many growth signaling …

Background Increasing evidence indicates that the dysregulation of microRNAs (miRNAs)
play critical roles tumor progression and metastasis, but very few papers had reported the …

Acute myeloid leukemia (AML) is a heterogeneous hematopoietic neoplasm which results in
clonal proliferation of abnormally differentiated hematopoietic cells. In this review …

Alzheimer's disease (AD) is a complex neurodegenerative disorder involving dysregulation
of many biological pathways at multiple levels. Classical epigenetic mechanisms, including …

MicroRNAs (miRNAs) are conserved noncoding RNAs that function as posttranscriptional
regulators of gene expression. miR-9 is one of the most abundant miRNAs in the brain …