Pharmaceutical research and development and manufacturing can widely benefit from a
microgravity environment. Although the use of microgravity to improve control over the size …

Proteins are functional macromolecules in living organisms including mammals and thus
human beings. They are involved in almost all biological processes, either as the main …

Experimental and theoretical investigations on protein crystal nucleation are reviewed.
Various experimental applications of the classical principle, which requires separation of the …

With the increase in applications of protein-based medicines approved and developed,
downstream manufacturing of biopharmaceuticals has challenges of finding cost-effective …

One small RNA plant virus and three monomeric and small molecular mass proteins (M r=
14500− 22200) were crystallized in a centrifuge at gravity levels between 1000 and 22000 g …

Static light scattering and multiwell microbatch crystallization experiments have been used
to determine how apoferritin crystal growth kinetics and final crystal size depend on …

Catalyzing life-sustaining reactions, proteins are composed by 20 different amino acids that
fold into a compact yet flexible three-dimensional architecture, which dictates what their …

Heterogeneous (on‐glass) protein crystal nucleation was separated from the bulk one in
systems of thin protein solution layers, confined between two glass plates of custom made …

In spite of recent progress in the understanding of the nucleation process and the
exploitation of new crystallization methods the understanding of the crystallization process of …

In this investigation, fluid dynamics of a spherical particle in a rotating liquid sphere is
studied. Such problems arise during protein crystal growth by the containerless approach in …