Cerebral ischemia and subsequent reperfusion, leading to reduced blood supply to specific
brain areas, remain significant contributors to neurological damage, disability, and mortality …

Sepsis-induced central nervous system damage is called sepsis-associated
encephalopathy (SAE). In addition to neuroinflammation, oxidative stress and apoptosis act …

Abstract Quercetin (QE; 3, 5, 7, 3′, 4′-pentahydroxyflavone), a well-known flavonoid, has
been shown to prevent against neurodegenerative disorders and ischemic insults. However …

Research reports using animal models of ischemic insults have demonstrated that
oxcarbazepine (a carbamazepine analog: one of the anticonvulsant compounds) extends …

Epilepsy is characterized by recurrent epileptic seizures, and its effective management
continues to be a therapeutic challenge. Oxidative stress and local inflammatory response …

The lithium-pilocarpine model in rats is commonly used to study the characteristic events of
acute status epilepticus (SE), epileptogenesis and temporal lobe epilepsy (TLE). Here we …

Background Parkinson's disease (PD) is a chronic and progressive neurodegenerative
disorder that primarily affects the motor system. Although there are several treatments …

In neonates supraphysiological oxygen therapy has been demonstrated to cause neuronal
death in hippocampus, prefrontal cortex, parietal cortex, and retrosplenial cortex. There is a …

Highlights•OXC post-treatment in transient ischemia protects neurons in hippocampal
CA1.•OXC attenuates ischemia-induced oxidative stress in ischemic CA1.•OXC suppresses …

Objective Currently, lacosamide (LCM) is not approved for use in status epilepticus (SE) but
several shreds of evidence are available to support its use. The present study was …