Glucocorticoids and fetal programming part 1: outcomes

VG Moisiadis, SG Matthews - Nature Reviews Endocrinology, 2014 - nature.com
Fetal development is a critical period for shaping the lifelong health of an individual.
However, the fetus is susceptible to internal and external stimuli that can lead to adverse …

Fetal programming of hypothalamo‐pituitary‐adrenal function: prenatal stress and glucocorticoids

A Kapoor, E Dunn, A Kostaki… - The Journal of …, 2006 - Wiley Online Library
Prenatal stress (PS) and maternal exposure to exogenous glucocorticoids can lead to
permanent modification of hypothalamo‐pituitary‐adrenal (HPA) function and stress‐related …

[图书][B] Cerebral palsies: epidemiology and causal pathways

FJ Stanley, E Blair, E Alberman, ED Alberman - 2000 - books.google.com
This is a clinical text about the commonest physical disability-the cerebral palsies. It follows
up on the authors' earlier work The Epidemiology of the Cerebral Palsies, and its focus is still …

Different corticosteroids and regimens for accelerating fetal lung maturation for women at risk of preterm birth

FC Brownfoot, DI Gagliardi, E Bain… - Cochrane Database …, 2013 - cochranelibrary.com
Background Despite the widespread use of antenatal corticosteroids to prevent respiratory
distress syndrome in preterm infants, there is currently no consensus as to the type of …

Multiple courses of antenatal corticosteroids for preterm birth (MACS): a randomised controlled trial

KE Murphy, ME Hannah, AR Willan, SA Hewson… - The Lancet, 2008 - thelancet.com
Background One course of antenatal corticosteroids reduces the risk of respiratory distress
syndrome and neonatal death. Weekly doses given to women who remain undelivered after …

Repeated antenatal corticosteroids: size at birth and subsequent development

NP French, R Hagan, SF Evans, M Godfrey… - American journal of …, 1999 - Elsevier
Objective: The objective was to study the effects of repeated antenatal corticosteroids on
birth size, growth, and development in preterm infants. Study Design: This observational …

Long-term outcomes after repeat doses of antenatal corticosteroids

RJ Wapner, Y Sorokin, L Mele, F Johnson… - … England Journal of …, 2007 - Mass Medical Soc
Background Previous trials have shown that repeat courses of antenatal corticosteroids
improve some neonatal outcomes in preterm infants but reduce birth weight and increase …

Fetal programming of hypothalamic–pituitary–adrenal (HPA) axis function and behavior by synthetic glucocorticoids

A Kapoor, S Petropoulos, SG Matthews - Brain research reviews, 2008 - Elsevier
Reduced fetal growth has been closely associated with an increased risk for the
development of chronic disease in later life. Accumulating evidence indicates that fetal …

Effect of corticosteroids on brain growth in fetal sheep

WL Huang, LD Beazley, JA Quinlivan, SF Evans… - Obstetrics & …, 1999 - Elsevier
Objective: To compare the effects of single and repeated courses of corticosteroids on brain
growth in fetal sheep. Methods: Pregnant sheep were given intramuscular betamethasone …

Prenatal synthetic glucocorticoid treatment changes DNA methylation states in male organ systems: multigenerational effects

A Crudo, S Petropoulos, VG Moisiadis, M Iqbal… - …, 2012 - academic.oup.com
Prenatal synthetic glucocorticoids (sGC) are administered to pregnant women at risk of
delivering preterm, approximately 10% of all pregnancies. Animal studies have …