Small-angle X-ray scattering (SAXS) is increasingly used to characterize the structure and
interactions of biological macromolecules and their complexes in solution. Although still a …

To understand the cell, we need to determine the macromolecular assembly structures,
which may consist of tens to hundreds of components. First, we review the varied …

A major challenge in structural biology is to determine the configuration of domains and
proteins in multidomain proteins and assemblies, respectively. All available data should be …

Computational modeling can provide a wealth of insight into how energy flow in proteins
mediates protein function. Computational methods can also address fundamental questions …

We present a coarse residue-based computational method to rapidly compute the solution
scattering profile from a protein with dynamical fluctuations. The method is built upon a …

In this paper, we report a new method for coarse-grained elastic normal-mode analysis. The
purpose is to overcome a long-standing problem in the conventional analysis called the tip …

Small-angle X-ray scattering (SAXS) experiments provide valuable structural data for
biomolecules in solution. We develop a highly efficient maximum entropy approach to fit …

In this paper, we report a knowledge‐based potential function, named the OPUS‐Ca
potential, that requires only Cα positions as input. The contributions from other atomic …

In the last few years, SAXS of biological materials has been rapidly evolving and promises to
move structural analysis to a new level. Recent innovations in SAXS data analysis allow ab …

Small-angle x-ray scattering (SAXS) is a powerful technique widely used to explore
conformational states and transitions of biomolecular assemblies in solution. For accurate …