[HTML][HTML] Lead-DBS v3. 0: Mapping deep brain stimulation effects to local anatomy and global networks

C Neudorfer, K Butenko, S Oxenford, N Rajamani… - Neuroimage, 2023 - Elsevier
Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …

Deep brain stimulation: emerging tools for simulation, data analysis, and visualization

K Wårdell, T Nordin, D Vogel, P Zsigmond… - Frontiers in …, 2022 - frontiersin.org
Deep brain stimulation (DBS) is a well-established neurosurgical procedure for movement
disorders that is also being explored for treatment-resistant psychiatric conditions. This …

Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia

A Horn, MM Reich, S Ewert, N Li… - Proceedings of the …, 2022 - National Acad Sciences
Dystonia is a debilitating disease with few treatment options. One effective option is deep
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …

Probabilistic mapping of deep brain stimulation: insights from 15 years of therapy

GJB Elias, A Boutet, SE Joel, J Germann… - Annals of …, 2021 - Wiley Online Library
Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …

Therapies to restore consciousness in patients with severe brain injuries: a gap analysis and future directions

BL Edlow, LRD Sanz, L Polizzotto, N Pouratian… - Neurocritical care, 2021 - Springer
Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …

[HTML][HTML] Normative vs. patient-specific brain connectivity in deep brain stimulation

Q Wang, H Akram, M Muthuraman… - Neuroimage, 2021 - Elsevier
Brain connectivity profiles seeding from deep brain stimulation (DBS) electrodes have
emerged as informative tools to estimate outcome variability across DBS patients. Given the …

Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation

B Hollunder, JL Ostrem, IA Sahin, N Rajamani… - Nature …, 2024 - nature.com
Frontal circuits play a critical role in motor, cognitive and affective processing, and their
dysfunction may result in a variety of brain disorders. However, exactly which frontal …

[HTML][HTML] Deep brain stimulation: Imaging on a group level

S Treu, B Strange, S Oxenford, WJ Neumann, A Kühn… - Neuroimage, 2020 - Elsevier
Abstract Deep Brain Stimulation (DBS) is an established treatment option for movement
disorders and is under investigation for treatment in a growing number of other brain …

A unified functional network target for deep brain stimulation in obsessive-compulsive disorder

N Li, B Hollunder, JC Baldermann, A Kibleur, S Treu… - Biological …, 2021 - Elsevier
Background Multiple deep brain stimulation (DBS) targets have been proposed for treating
intractable obsessive-compulsive disorder (OCD). Here, we investigated whether stimulation …

Subthalamic and pallidal deep brain stimulation: are we modulating the same network?

L Sobesky, L Goede, VJJ Odekerken, Q Wang, N Li… - Brain, 2022 - academic.oup.com
The subthalamic nucleus and internal pallidum are main target sites for deep brain
stimulation in Parkinson's disease. Multiple trials that investigated subthalamic versus …