Personalizing neoadjuvant immune-checkpoint inhibition in patients with melanoma

MW Lucas, JM Versluis, EA Rozeman… - Nature Reviews Clinical …, 2023 - nature.com
Neoadjuvant immune-checkpoint inhibition is a promising emerging treatment approach for
patients with surgically resectable macroscopic stage III melanoma. The neoadjuvant setting …

[HTML][HTML] T cell-engaging bispecific antibodies targeting gp100 and PRAME: expanding application from uveal melanoma to cutaneous melanoma

R Reschke, AH Enk, JC Hassel - Pharmaceutics, 2024 - mdpi.com
Uveal melanoma represents a rare and aggressive subtype of melanoma with limited
treatment options and poor prognosis, especially in the metastatic setting. Tebentafusp, a …

Leveraging STING, batf3 dendritic cells, CXCR3 ligands, and other components related to innate immunity to induce A “Hot” Tumor microenvironment that is …

R Reschke, DJ Olson - Cancers, 2022 - mdpi.com
Simple Summary The conceptualization of a “hot” tumor microenvironment has been
characterized by mainly T cell infiltration, whereas,“cold” or “immune-deserted” tumors were …

Risk stratification and clinical characteristics of patients with late recurrence of melanoma (> 10 years)

R Reschke, K Dumann, M Ziemer - Journal of Clinical Medicine, 2022 - mdpi.com
Background: Most patients with high-risk melanomas develop metastasis within the first few
years after diagnosis. However, late recurrence of melanoma is seen in patients that …

Immune checkpoint inhibition and targeted therapy for melanoma: A patient‐oriented cross‐sectional comparative multicentre study

A Thiem, P Mashhadiakbar, C Cussigh… - Journal of the …, 2023 - Wiley Online Library
Background Choosing the adequate systemic treatment for melanoma is driven by clinical
parameters and personal preferences. Objective Evaluation of the impact of disease and …

A systematic review of patient-reported outcome measures for advanced skin cancer patients

ME Reinhardt, T Sun, CX Pan, CD Schmults… - Archives of …, 2023 - Springer
Many patient-reported outcome measures (PROMs) have been used to study quality of life
(QOL) in the skin cancer population. Advanced melanoma and non-melanoma skin cancer …

[HTML][HTML] The validity of the distress thermometer in patients with musculoskeletal tumors

FM Uhlenbruch, N Schopow, E Roschke, C Lycke… - Journal of Bone …, 2024 - Elsevier
Background Visits to an outpatient cancer clinic represent a challenging situation for
patients, which can trigger anxiety and helplessness in those affected. It is important to …

[PDF][PDF] Facial lipodystrophy after immunotherapy with Nivolumab

K Drexler, V Zenderowski… - Journal der …, 2021 - epub.uni-regensburg.de
Figure 1 Lipodystrophy of the cheeks and enophthalmos twelve weeks following twelve
months of adjuvant therapy with nivolumab. our patient with immune-mediated localized …

[PDF][PDF] Onkologische Systemtherapie bis zum bitteren Ende?

C Berking - JDDG: Journal der Deutschen Dermatologischen …, 2021 - scholar.archive.org
Onkologische Systemtherapie bis zum bitteren Ende? Page 1 Editorial 1259 © 2021 The
Authors. Journal der Deutschen Dermatologischen Gesellschaft published by John Wiley & …

Metastatic pigmented epithelioid melanocytoma in a 7-year-old female

CM Thielmann, S Ugurel… - … = Journal of the …, 2021 - pubmed.ncbi.nlm.nih.gov
Metastatic pigmented epithelioid melanocytoma in a 7-year-old female Metastatic pigmented
epithelioid melanocytoma in a 7-year-old female J Dtsch Dermatol Ges. 2021 …