Ari Helenius launched the field of enveloped virus fusion in endosomes with a seminal
paper in the Journal of Cell Biology in 1980. In the intervening years, a great deal has been …

Cellular membranes undergo continuous remodeling. Exocytosis and endocytosis,
mitochondrial fusion and fission, entry of enveloped viruses into host cells and release of the …

The N-terminal fusion peptide (residues 770–788) of an S2 glycoprotein of the severe acute
respiratory syndrome coronavirus (SARS-CoV), exposed upon receptor binding, is crucial …

We review the current state of membrane protein structure determination using solid-state
nuclear magnetic resonance (NMR) spectroscopy. Multidimensional magic-angle-spinning …

Sphingolipid synthesis involves a highly conserved biosynthetic pathway that produces
fundamental precursors of complex sphingolipids. The final reaction involves the insertion of …

Biomolecular applications of NMR spectroscopy are often merely associated with soluble
molecules or magnetic resonance imaging. However, since the late 1970s, solid‐state NMR …

Ionizable lipids are important compounds of modern therapeutic lipid nano-particles (LNPs).
One of the most promising ionizable lipids (or amine lipids) is DLin-MC3-DMA. Depending …

The human immunodeficiency virus (HIV) gp41 fusion domain plays a critical role in
membrane fusion during viral entry. A thorough understanding of the relationship between …

Fusion peptides comprise conserved hydrophobic domains absolutely required for the
fusogenic activity of glycoproteins from divergent virus families. After 30 years of intensive …

Starting from fertilization, through tissue growth, hormone secretion, synaptic transmission,
and sometimes morbid events of carcinogenesis and viral infections, membrane fusion …