Current understanding of pathogenesis and treatment of TMJ osteoarthritis

XD Wang, JN Zhang, YH Gan… - Journal of dental …, 2015 - journals.sagepub.com
Osteoarthritis is a common disease that can cause severe pain and dysfunction in any joint,
including the temporomandibular joint (TMJ). TMJ osteoarthritis (TMJOA) is an important …

Emerging potential of exosomes in regenerative medicine for temporomandibular joint osteoarthritis

YH Lee, HK Park, QS Auh, H Nah, JS Lee… - International journal of …, 2020 - mdpi.com
Exosomes are nanosized vesicles (30–140 nm) of endocytic origin that play important roles
in regenerative medicine. They are derived from cell membranes during endocytic …

Osteoimmunology of oral and maxillofacial diseases: translational applications based on biological mechanisms

C Alvarez, G Monasterio, F Cavalla… - Frontiers in …, 2019 - frontiersin.org
The maxillofacial skeleton is highly dynamic and requires a constant equilibrium between
the bone resorption and bone formation. The field of osteoimmunology explores the …

Recent advances in animal models, diagnosis, and treatment of temporomandibular joint osteoarthritis

D Wang, Y Qi, Z Wang, A Guo, Y Xu… - Tissue Engineering Part …, 2023 - liebertpub.com
Temporomandibular joint osteoarthritis (TMJOA) is a gradual degenerative jaw joint
condition. Until recent years, TMJOA is still relatively unrecognized and ineffective to be …

Comprehensive management of rheumatic diseases affecting the temporomandibular joint

L Covert, HV Mater, BL Hechler - Diagnostics, 2021 - mdpi.com
The temporomandibular joint (TMJ) is a synovial joint and thus is vulnerable to the afflictions
that may affect other joints in the fields of rheumatology and orthopedics. Too often …

TLR4 contributes to the damage of cartilage and subchondral bone in discectomy‐induced TMJOA mice

X Liu, H Cai, P Cao, Y Feng, H Jiang… - Journal of cellular …, 2020 - Wiley Online Library
The abundance of inflammatory mediators in injured joint indicates innate immune reactions
activated during temporomandibular joint osteoarthritis (TMJOA) progression. Toll‐like …

Aberrant activation of latent transforming growth factor-β initiates the onset of temporomandibular joint osteoarthritis

L Zheng, C Pi, J Zhang, Y Fan, C Cui, Y Zhou, J Sun… - Bone research, 2018 - nature.com
There is currently no effective medical treatment for temporomandibular joint osteoarthritis
(TMJ-OA) due to a limited understanding of its pathogenesis. This study was undertaken to …

Posteroanterior cephalometric changes in subjects with temporomandibular joint disorders

OC Almăşan, M Băciuţ, M Hedeşiu… - Dentomaxillofacial …, 2013 - academic.oup.com
Objectives The aim of the study was to establish the changes in posteroanterior
cephalometric variables in subjects with temporomandibular joint disorders (TMDs) …

Diagnostic criteria for temporomandibular joint osteoarthritis using standardized uptake value in single-photon emission computed tomography–computed …

JY Kim, C Lee, YL Park, JH Lee, YH Ryu, JK Huh - Scientific Reports, 2024 - nature.com
This study aimed to investigate the cutoff values of standardized uptake values (SUVs) and
their accuracy using single-photon emission computed tomography–computed tomography …

Osseous changes of the mandibular condyle affect backward-rotation of the mandibular ramus in Angle Class II orthodontic patients with idiopathic condylar resorption …

TS Kajii, T Fujita, Y Sakaguchi, K Shimada - CRANIO®, 2019 - Taylor & Francis
Objective: To evaluate whether osseous changes of the temporomandibular joint (TMJ)
condyle affect backward rotation of the mandibular ramus in Angle Class II orthodontic …