Various lines of evidence accumulated over the past 30 years indicate that the cerebellum,
long recognized as essential for motor control, also has considerable influence on …

Highlights•Advanced control theory highlights the role of sensory feedback for motor
function.•Goal-directed feedback begins in muscle activity∼ 60 ms after the limb is …

For more than two decades, there has been converging evidence for an essential role of the
cerebellum in non-motor functions. The cerebellum is not only important in learning and …

Recent work has shown that, when countering external forces, the nervous system adjusts
not only predictive (ie, feedforward) control of reaching but also reflex (ie, feedback) …

A hallmark of voluntary motor control is the ability to adjust motor patterns for novel
mechanical or visuomotor contexts. Recent work has also highlighted the importance of …

Cerebellar damage results in uncoordinated, variable and dysmetric movements known as
ataxia. Here we show that we can reliably model single-joint reaching trajectories of patients …

In order to perform accurate movements, the nervous system must transform sensory
feedback into motor commands that compensate for errors caused by motor variability and …

Accurate control of body posture is enforced by a multitude of corrective actions operating
over a range of time scales. The earliest correction is the short-latency reflex (SLR) which …

Learning a new motor task modifies feedforward (ie, voluntary) motor commands and such
learning also changes the sensitivity of feedback responses (ie, reflexes) to mechanical …

Although rigidity is a cardinal motor sign in patients with Parkinson's disease (PD), the
instrumental measurement of this clinical phenomenon is largely lacking, and its …