The anti-inflammatory mechanism of antidepressants–SSRIs, SNRIs

P Gałecki, J Mossakowska-Wójcik… - Progress in Neuro …, 2018 - Elsevier
The cytokine theory of depression no longer brings about any doubts. Experiments and
research studies conducted in the last ten years have confirmed that both physical and …

Off-target effects of antidepressants on vascular function and structure

A Dimoula, D Fotellis, E Aivalioti, D Delialis… - Biomedicines, 2021 - mdpi.com
Depression emerges as a risk factor for cardiovascular disease, and it is thought that
successful antidepressant treatment may reduce such a risk. Therefore, antidepressant …

Neurobehavioral and neurobiochemical effect of atomoxetine and N-acetylcysteine in streptozotocin diabetes induced endothelial dysfunction and related dementia

H Aggarwal, S Gupta, P Sharma, BM Sharma… - Physiology & …, 2022 - Elsevier
Metabolic conditions like diabetes, is a major risk factor for the development of dementia of
vascular origin. This study investigates the efficacy of atomoxetine (ATX) and N …

Neuroprotective effects of nicorandil in chronic cerebral hypoperfusion-induced vascular dementia

S Gupta, P Singh, B Sharma - Journal of Stroke and Cerebrovascular …, 2016 - Elsevier
Background Ischemia-induced chronic cerebral hypoperfusion (CCH) is associated with
reduced cerebral blood flow and vascular dementia (VaD). Brain mitochondrial potassium …

Physical activity, sleep disorders, and type of work in the prevention of cognitive function decline in patients with hypertension

M Zhang, H Jiao, C Wang, Y Qu, S Lv, D Zhao… - BMC Public Health, 2023 - Springer
Background Hypertensive patients are likelier to have cognitive function decline (CFD). This
study aimed to explore physical activity level, sleep disorders, and type of work that …

A comparative, single-blind, randomized study on quetiapine and aripiperazole augmentation in treatment of selective serotonin reuptake inhibitor refractory …

A Talaei, FF Hosseini, Z Aghili… - Canadian Journal of …, 2020 - cdnsciencepub.com
Obsessive-compulsive disorder (OCD) is a chronic psychiatric disorder, of unknown
etiology, that affects 2.5% of the population. An appropriate therapeutic response to …

Selective modulator of cannabinoid receptor type 2 reduces memory impairment and infarct size during cerebral hypoperfusion and vascular dementia

S Jayant, B Sharma - Current Neurovascular Research, 2016 - ingentaconnect.com
Vascular dementia is the highly devastating neurodegenerative disorder after Alzheimer's
disease (AD) and mainly found in aged people but the effectual therapeutic target is still not …

[HTML][HTML] The protective effects of Irbesartan in cognitive impairment in hypertension

S Hao, Q He, Y Yuan, Q Mu - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Vascular cognitive impairment (VCI) is claimed as the second most common type of
dementia after Alzheimer's disease (AD), in which hypertension is a critical inducer …

Neuroprotective effect of duloxetine on chronic cerebral hypoperfusion-induced hippocampal neuronal damage

JA Park, CH Lee - Biomolecules & Therapeutics, 2017 - pmc.ncbi.nlm.nih.gov
Chronic cerebral hypoperfusion (CCH), which is associated with onset of vascular dementia,
causes cognitive impairment and neuropathological alterations in the brain. In the present …

Montelukast Ameliorates 2K1C-Hypertension Induced Endothelial Dysfunction and Associated Vascular Dementia

S Gupta, P Singh, B Sharma - Current Hypertension Reviews, 2024 - ingentaconnect.com
Background: Declined kidney function associated with hypertension is a danger for cognitive
deficits, dementia, and brain injury. Cognitive decline and vascular dementia (VaD) are …