Genetic polymorphisms linked to susceptibility to malaria

A Driss, JM Hibbert, NO Wilson, SA Iqbal… - Malaria journal, 2011 - Springer
The influence of host genetics on susceptibility to Plasmodium falciparum malaria has been
extensively studied over the past twenty years. It is now clear that malaria parasites have …

How glycosylation affects glycosylation: the role of N-glycans in glycosyltransferase activity

K Mikolajczyk, R Kaczmarek, M Czerwinski - Glycobiology, 2020 - academic.oup.com
N-glycosylation is one of the most important posttranslational modifications of proteins. It
plays important roles in the biogenesis and functions of proteins by influencing their folding …

Dynamic transcriptome reveals the mechanism of liver injury caused by DHAV-3 infection in pekin duck

J Cao, Y Zhang, Y Chen, S Liang, D Liu, W Fan… - Frontiers in …, 2020 - frontiersin.org
Duck hepatitis A virus 3 (DHAV-3) is a wild endemic virus, which seriously endangers the
duck industry in China. The present study aims to elucidate the mechanism of duck …

Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria

V Holmberg, P Onkamo, E Lahtela, P Lahermo… - Malaria journal, 2012 - Springer
Background Innate immunity plays a crucial role in the host defense against malaria
including Plasmodium falciparum malaria in pregnancy, but the roles of the various …

Gene-Gene Interaction and Functional Impact of Polymorphisms on Innate Immune Genes in Controlling Plasmodium falciparum Blood Infection Level

M Basu, T Das, A Ghosh, S Majumder, AK Maji… - 2012 - journals.plos.org
Genetic variations in toll-like receptors and cytokine genes of the innate immune pathways
have been implicated in controlling parasite growth and the pathogenesis of Plasmodium …

Genome-wide association studies on malaria in Sub-Saharan Africa: a scoping review

M Akoth, J Odhiambo, B Omolo - medRxiv, 2024 - medrxiv.org
Background: Malaria remains one of the leading causes of death in Sub-Saharan Africa
(SSA). The scoping review mapped evidence in research on existing studies on malaria …

Comparison of expression systems for human fucosyltransferase IX

C Stacke, P Ziegelmüller, U Hahn - European journal of cell biology, 2010 - Elsevier
Human fucosyltransferase IX (hFucT-IX) is a highly conserved α1, 3 fucosyltransferase with
a distinct acceptor and site specificity. hFucT-IX catalyses the transfer of activated fucose to a …

A targeted association study of immunity genes and networks suggests novel associations with placental malaria infection

M Sikora, H Laayouni, C Menendez, A Mayor… - PLoS …, 2011 - journals.plos.org
A large proportion of the death toll associated with malaria is a consequence of malaria
infection during pregnancy, causing up to 200,000 infant deaths annually. We previously …

Clinical and pathophysiological characterization of patients with acutely decompensated cirrhosis and acute-on-chronic liver failure

G Zaccherini - 2022 - amsdottorato.unibo.it
In the last decade, our understanding of the pathophysiological mechanisms underlying
decompensated cirrhosis has greatly increased. Moreover, acute-on-chronic liver failure …

[图书][B] Association Analysis of Additive Effects and Epistasis Between Human Candidate Malaria Protective Genes

CM Ndila - 2015 - search.proquest.com
Malaria is a major cause of childhood death in Africa and host genetic factors play a key role
in determining survival from this disease. Although many candidate loci have been …