Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

Physical forces regulate numerous biological processes during development, physiology,
and pathology. Forces between the external environment and intracellular actin cytoskeleton …

Platelets promote metastasis, however, their role in tumor growth remains controversial.
Here, we investigated the effect of platelet interactions with colorectal tumor cells. Platelets …

The transcription factor Twist1 is involved in the epithelial–mesenchymal transition and
contributes to cancer metastasis through mostly unknown mechanisms. In colorectal cancer …

Cell-cell adhesion molecules (cadherins) and cell-extracellular matrix adhesion proteins
(integrins) play a critical role in the regulation of cancer invasion and metastasis. Although …

RGD peptide can be found in cell adhesion and signaling proteins, such as fibronectin,
vitronectin, and fibrinogen. RGD peptides' principal function is to facilitate cell adhesion by …

The Hippo pathway regulates the down-stream target Yes-associated protein (YAP) to
maintain organ homeostasis, which is commonly inactivated in many types of cancers …

In cancer photodynamic therapy (PDT), a photosensitizer taken up by cancer cells can
generate reactive oxygen species upon near-infrared light activation to induce cancer cell …

Cadherin 6 (CDH6) is significantly overexpressed in advanced ovarian and renal cancers.
However, the role of CDH6 in cancer metastasis is largely unclear. Here, we investigated the …

We propose a new cadherin family classification comprising epithelial cadherins (cadherin
17 [CDH17], cadherin 16, VE-cadherin, cadherin 6 and cadherin 20) containing RGD motifs …