Antimicrobial peptides: a new frontier in antifungal therapy

G Buda De Cesare, SA Cristy, DA Garsin, MC Lorenz - MBio, 2020 - Am Soc Microbiol
Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …

Multitalented synthetic antimicrobial peptides and their antibacterial, antifungal and antiviral mechanisms

T Vanzolini, M Bruschi, AC Rinaldi, M Magnani… - International Journal of …, 2022 - mdpi.com
Despite the great strides in healthcare during the last century, some challenges still
remained unanswered. The development of multi-drug resistant bacteria, the alarming …

Fusarium fruiting body microbiome member Pantoea agglomerans inhibits fungal pathogenesis by targeting lipid rafts

S Xu, YX Liu, T Cernava, H Wang, Y Zhou, T Xia… - Nature …, 2022 - nature.com
Plant-pathogenic fungi form intimate interactions with their associated bacterial microbiota
during their entire life cycle. However, little is known about the structure, functions and …

Activity and mechanism of action of antifungal peptides from microorganisms: a review

T Li, L Li, F Du, L Sun, J Shi, M Long, Z Chen - Molecules, 2021 - mdpi.com
Harmful fungi in nature not only cause diseases in plants, but also fungal infection and
poisoning when people and animals eat food derived from crops contaminated with them …

Epinecidin-1, a marine antifungal peptide, inhibits Botrytis cinerea and delays gray mold in postharvest peaches

L Fan, Y Wei, Y Chen, S Jiang, F Xu, C Zhang, H Wang… - Food Chemistry, 2023 - Elsevier
This study investigated the mechanism of epinecidin-1 against Botrytis cinerea, in vitro, and
its effectiveness at inhibiting gray mold on postharvest peach fruit. We found that in vitro …

[HTML][HTML] Microbial lipopeptides: Properties, mechanics and engineering for novel lipopeptides

SM Sreedharan, N Rishi, R Singh - Microbiological Research, 2023 - Elsevier
Microorganisms produce active surface agents called lipopeptides (LPs) which are
amphiphilic in nature. They are cyclic or linear compounds and are predominantly isolated …

Mycosubtilin Produced by Bacillus subtilis ATCC6633 Inhibits Growth and Mycotoxin Biosynthesis of Fusarium graminearum and Fusarium verticillioides

C Yu, X Liu, X Zhang, M Zhang, Y Gu, Q Ali… - Toxins, 2021 - mdpi.com
Fusarium graminearum and Fusarium verticillioides are fungal pathogens that cause
diseases in cereal crops, such as Fusarium head blight (FHB), seedling blight, and stalk rot …

Bacillus atrophaeus NX-12 Utilizes Exosmotic Glycerol from Fusarium oxysporum f. sp. cucumerinum for Fengycin Production

J Xue, L Sun, H Xu, Y Gu, P Lei - Journal of Agricultural and Food …, 2023 - ACS Publications
Bacillus strains are widely used as biological control agents to protect plants from fungal
pathogens. However, whether Bacillus can exploit fungal pathogens to increase its …

Improved the lipopeptide production of Bacillus amyloliquefaciens HM618 under co-culture with the recombinant Corynebacterium glutamicum producing high-level …

XY Chen, HZ Sun, B Qiao, CH Miao, ZJ Hou… - Bioresource …, 2022 - Elsevier
The application of antibacterial lipopeptides is limited by high cost and low yield. Herein, the
exogenous L-proline significantly improved lipopeptide production by Bacillus …

Nature's antimicrobial arsenal: non-ribosomal peptides from pgpb for plant pathogen biocontrol

A Ranjan, VD Rajput, EV Prazdnova, M Gurnani… - Fermentation, 2023 - mdpi.com
Non-ribosomal peptides (NRPs) are a diverse group of bioactive compounds synthesized by
microorganisms, and their antimicrobial properties make them ideal candidates for use as …