Purpose Mammalian oogenesis and folliculogenesis share a dynamic connection that is
critical for gamete development. For maintenance of quiescence or follicular activation …

Development of early follicles, especially the activation of primordial follicles, is strictly
modulated by a network of signaling pathways. Recent advance in ovarian physiology has …

Context: Recently, two patients with primary ovarian insufficiency (POI) delivered healthy
babies after in vitro activation (IVA) treatment followed by auto-transplantation of frozen …

The ovary is a dynamic organ that undergoes some of the most dramatic changes in
structure and function of any adult human tissue. The follicles are the major endocrine and …

The mammalian ovary has two main functions—producing mature oocytes for fertilization
and secreting hormones for maintaining the ovarian endocrine functions. Both functions are …

Purpose The purpose of this study was to summarize the latest advances and successes in
the field of ovarian tissue cryopreservation while identifying gaps in current knowledge that …

In vitro ovarian cortical tissue culture, followed by culture of isolated secondary follicles, is a
promising future option for production of mature oocytes. Although efforts have been made …

In female mammals, the majority of primordial follicles (PFs) are physiologically quiescent,
and only a few of them are activated and enter the growing follicle pool. Specific molecules …

Understanding and control of the massive and accelerated follicular growth that occurs
during in vitro culture of ovarian tissue is a crucial step toward the development of efficient …

Abstract Ethnopharmacological relevance Dingkun Pill (DKP) is a traditional Chinese
medicine that has been shown to have beneficial effects on reproductive function. However …