Introduction Myocardial infarction is coronary artery-related heart disease, and the leading
cause of mortality globally. Circular RNAs (circRNAs) are a new type of regulatory RNAs and …

High mobility group box 1 (HMGB1) presents in almost all somatic cells as a component of
the cell nucleus. It is necessary for transcription regulation during cell development. Recent …

Although recent progress in medicine has substantially reduced cardiovascular diseases
(CVDs)-related mortalities, current therapeutics have failed miserably to be beneficial for all …

Background Gene therapy has been proposed as a strategy to induce cardiac regeneration
following acute myocardial infarction (AMI). Given that Tbx20, a transcription factor of the T …

Intervertebral disc degeneration (IDD) remains a leading cause of adult disability. High
mobility group box l (HMGB1) is a nuclear DNA-binding protein and acts as a central …

Objective: This study aims to investigate the pathogenic role of TBX20 gene mutations in
congenital heart disease (CHD), evaluate their impact on cardiac development and function …

Adult mammalian cardiomyocytes show scarce division ability, which makes the heart
ineffective in replacing lost contractile cells after ischemic cardiomyopathy. In the past …

This chapter presents a brief overview of new insights into the pathogenesis of
cerebrovascular disorders (stroke, cerebral hemorrhage) and coronary artery diseases (eg …

2023-03-20 Assigned to OXFORD UNIVERSITY INNOVATION LIMITED reassignment
OXFORD UNIVERSITY INNOVATION LIMITED ASSIGNMENT OF ASSIGNORS INTEREST …