Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment
W Yang, T Li, S Liao, J Zhou, L Huang - TrAC Trends in Analytical …, 2024 - Elsevier
Abstract Organs-on-chips (OoCs) are in vitro models that simulate the anatomical and
physiological structure of human organs at the micro-scale level. With the advantages of …
physiological structure of human organs at the micro-scale level. With the advantages of …
The evolution of in vitro models of lung fibrosis: promising prospects for drug discovery
E Kolanko, A Cargnoni, A Papait… - European …, 2024 - Eur Respiratory Soc
Lung fibrosis is a complex process, with unknown underlying mechanisms, involving various
triggers, diseases and stimuli. Different cell types (epithelial cells, endothelial cells …
triggers, diseases and stimuli. Different cell types (epithelial cells, endothelial cells …
Modeling mechanical activation of macrophages during pulmonary fibrogenesis for targeted anti-fibrosis therapy
Pulmonary fibrosis is an often fatal lung disease. Immune cells such as macrophages were
shown to accumulate in the fibrotic lung, but their contribution to the fibrosis development is …
shown to accumulate in the fibrotic lung, but their contribution to the fibrosis development is …
[HTML][HTML] In Vitro Modeling of Idiopathic Pulmonary Fibrosis: Lung-on-a-Chip Systems and Other 3D Cultures
Idiopathic pulmonary fibrosis (IPF) is a lethal disorder characterized by relentless
progression of lung fibrosis that causes respiratory failure and early death. Currently, no …
progression of lung fibrosis that causes respiratory failure and early death. Currently, no …
[HTML][HTML] Proteomic analysis reveals the aging-related pathways contribute to pulmonary fibrogenesis
T Zhang, X Yuan, M Jiang, B Liu, N Zhai… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Aging usually causes lung-function decline and susceptibility to chronic lung diseases, such
as pulmonary fibrosis. However, how aging affects the lung-fibrosis pathways and leads to …
as pulmonary fibrosis. However, how aging affects the lung-fibrosis pathways and leads to …