[HTML][HTML] An overview of systemic lupus erythematosus (SLE) pathogenesis, classification, and management
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem
involvement. It is multifactorial and involves epigenetic, genetic, ecological, and …
involvement. It is multifactorial and involves epigenetic, genetic, ecological, and …
Indirect treatment comparison of anifrolumab efficacy versus belimumab in adults with systemic lupus erythematosus
IN Bruce, S Golam, J Steenkamp… - Journal of …, 2022 - becarispublishing.com
Aim: Assess the comparative efficacy of anifrolumab 300 mg versus belimumab 10 mg/kg in
adults with moderate-to-severe systemic lupus erythematosus (SLE) receiving standard …
adults with moderate-to-severe systemic lupus erythematosus (SLE) receiving standard …
COVID-19 vaccine does not increase the risk of disease flare-ups among patients with autoimmune and immune-mediated diseases
L Pinte, F Negoi, GD Ionescu, S Caraiola… - Journal of Personalized …, 2021 - mdpi.com
Background: Reports describing post-vaccine autoimmune phenomena, in previously
healthy individuals, increased the concerns regarding the risk of disease flare-ups in …
healthy individuals, increased the concerns regarding the risk of disease flare-ups in …
Hydroxychloroquine dose per ophthalmology guidelines and the risk of systemic lupus erythematosus flares
Methods| We identified patients with SLE from Massachusetts General Hospital who had 2
or more rheumatology visits and used hydroxychloroquine between January 1, 2016, and …
or more rheumatology visits and used hydroxychloroquine between January 1, 2016, and …
Epidemiology and damage accrual of systemic lupus erythematosus in central Sweden: a single‐center population‐based cohort study over 14 years from …
Objective Variations in prevalence and incidence of systemic lupus erythematosus (SLE)
within a geographically defined area of central Sweden over a time period of 14 years were …
within a geographically defined area of central Sweden over a time period of 14 years were …
Reference range of hydroxychloroquine blood levels that can reduce odds of active lupus and prevent flares
Objective Recent data show that lower hydroxychloroquine (HCQ) doses are associated
with a two‐to six‐fold higher risk of lupus flares. Thus, establishing an effective reference …
with a two‐to six‐fold higher risk of lupus flares. Thus, establishing an effective reference …
Clinical response trajectories and drug persistence in systemic lupus erythematosus patients on belimumab treatment: A real-life, multicentre observational study
M Nikoloudaki, D Nikolopoulos, S Koutsoviti… - Frontiers in …, 2023 - frontiersin.org
Objective To obtain real-world data on outcomes of belimumab treatment and respective
prognostic factors in patients with systemic lupus erythematosus (SLE). Methods …
prognostic factors in patients with systemic lupus erythematosus (SLE). Methods …
Concordance and discordance in SLE clinical trial outcome measures: analysis of three anifrolumab phase 2/3 trials
Objectives In the anifrolumab systemic lupus erythematosus (SLE) trial programme, there
was one trial (TULIP-1) in which BILAG-based Composite Lupus Assessment (BICLA) …
was one trial (TULIP-1) in which BILAG-based Composite Lupus Assessment (BICLA) …
Immunogenicity and safety of mixed COVID-19 vaccine regimens in patients with immune-mediated inflammatory diseases: a single-centre prospective cohort study
CA Hitchon, C Mesa, CN Bernstein, RA Marrie… - BMJ open, 2023 - bmjopen.bmj.com
Objective Among persons with immune-mediated inflammatory diseases (IMIDs) who
received SARS-CoV-2 vaccines, we compared postvaccine antibody responses and IMID …
received SARS-CoV-2 vaccines, we compared postvaccine antibody responses and IMID …
Clinician-reported outcome measures in lupus trials: a problem worth solving
K Connelly, V Golder… - The Lancet …, 2021 - thelancet.com
Systemic lupus erythematosus (SLE) remains a disease of high unmet clinical need.
Because of substantial patient heterogeneity, the execution of clinical trials that successfully …
Because of substantial patient heterogeneity, the execution of clinical trials that successfully …