An overview of pre‐ribosomal RNA processing in eukaryotes
AK Henras, C Plisson‐Chastang… - Wiley …, 2015 - Wiley Online Library
Ribosomal RNAs are the most abundant and universal noncoding RNAs in living organisms.
In eukaryotes, three of the four ribosomal RNAs forming the 40S and 60S subunits are borne …
In eukaryotes, three of the four ribosomal RNAs forming the 40S and 60S subunits are borne …
Uncovering the assembly pathway of human ribosomes and its emerging links to disease
KE Bohnsack, MT Bohnsack - The EMBO journal, 2019 - embopress.org
The essential cellular process of ribosome biogenesis is at the nexus of various signalling
pathways that coordinate protein synthesis with cellular growth and proliferation. The fact …
pathways that coordinate protein synthesis with cellular growth and proliferation. The fact …
The human RNA-binding proteome and its dynamics during translational arrest
J Trendel, T Schwarzl, R Horos, A Prakash, A Bateman… - Cell, 2019 - cell.com
Proteins and RNA functionally and physically intersect in multiple biological processes,
however, currently no universal method is available to purify protein-RNA complexes. Here …
however, currently no universal method is available to purify protein-RNA complexes. Here …
The exosome is recruited to RNA substrates through specific adaptor proteins
The exosome regulates the processing, degradation, and surveillance of a plethora of RNA
species. However, little is known about how the exosome recognizes and is recruited to its …
species. However, little is known about how the exosome recognizes and is recruited to its …
Small non-coding RNAs derived from eukaryotic ribosomal RNA
M Lambert, A Benmoussa, P Provost - Non-coding RNA, 2019 - mdpi.com
The advent of RNA-sequencing (RNA-Seq) technologies has markedly improved our
knowledge and expanded the compendium of small non-coding RNAs, most of which derive …
knowledge and expanded the compendium of small non-coding RNAs, most of which derive …
Pre-ribosomal RNA processing in human cells: from mechanisms to congenital diseases
Ribosomal RNAs, the most abundant cellular RNA species, have evolved as the structural
scaffold and the catalytic center of protein synthesis in every living organism. In eukaryotes …
scaffold and the catalytic center of protein synthesis in every living organism. In eukaryotes …
The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis
C Zorbas, E Nicolas, L Wacheul, E Huvelle… - Molecular biology of …, 2015 - Am Soc Cell Biol
At the heart of the ribosome lie rRNAs, whose catalytic function in translation is subtly
modulated by posttranscriptional modifications. In the small ribosomal subunit of budding …
modulated by posttranscriptional modifications. In the small ribosomal subunit of budding …
Human NOP2/NSUN1 regulates ribosome biogenesis through non-catalytic complex formation with box C/D snoRNPs
Methylcytosine (m5C) is a base modification broadly found on various RNAs in the human
transcriptome. In eukaryotes, m5C is catalyzed by enzymes of the NSUN family composed of …
transcriptome. In eukaryotes, m5C is catalyzed by enzymes of the NSUN family composed of …
Comparison of preribosomal RNA processing pathways in yeast, plant and human cells–focus on coordinated action of endo‐and exoribonucleases
Proper regulation of ribosome biosynthesis is mandatory for cellular adaptation, growth and
proliferation. Ribosome biogenesis is the most energetically demanding cellular process …
proliferation. Ribosome biogenesis is the most energetically demanding cellular process …
SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing
SIRT7 is an NAD+-dependent protein deacetylase with important roles in ribosome
biogenesis and cell proliferation. Previous studies have established that SIRT7 is associated …
biogenesis and cell proliferation. Previous studies have established that SIRT7 is associated …