Focal cerebral ischemia results in an ischemic core surrounded by the peri‐infarct region
(penumbra). Most research attention has been focused on penumbra while the pattern of …

MRI-based oxygen extraction fraction imaging has a great potential benefit in the selection
of clinical strategies for ischemic stroke patients. This study aimed to evaluate the …

Ischemic stroke not only induces neuron death in the infarct area but also structural and
functional damage of the surviving neurons in the surrounding peri-infarct area. In the …

Purpose To improve accuracy and speed of quantitative susceptibility mapping plus
quantitative blood oxygen level‐dependent magnitude (QSM+ qBOLD or QQ)‐based …

Methylene blue (MB) USP, which has energy-enhancing and antioxidant properties, is
currently used to treat methemoglobinemia and cyanide poisoning in humans. We recently …

In neonatal hypoxic-ischemic brain damage (HIBD), in addition to damage caused by
hypoxia and ischemia, over-activation of inflammation leads to further deterioration of the …

Globally, stroke is one of the leading causes of death and significant contributors to
disability. Gaining a thorough comprehension of the underlying pathogenic processes is …

Objective To investigate the protective effect of neuroprotection against transient focal
cerebral ischemia of the extract from Tianma (Rhizoma Gastrodiae) and the possible …

In the clinic delayed post-conditioning would represent an attractive strategy for the survival
of vulnerable neurons after an ischemic event. In this paper we studied the impact of …

The successful implementation of remote ischaemic conditioning as a clinical
neuroprotective strategy requires a thorough understanding of its basic principles, which can …